A Review on Regenerative Endodontics
Background and Aim : Regenerative endodontics with the goal of replacing the lost dental tissues is developing fast. The aim of this study was to review the recent progressions, known limitations and advantages of regenerative treatments compared to other possible treatment modalities . Materials...
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| Format: | Article |
| Language: | English |
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Islamic Dental Association of Iran
2014-07-01
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| Series: | Journal of Islamic Dental Association of Iran |
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| Online Access: | http://jidai.ir/browse.php?a_code=A-10-1-775&slc_lang=en&sid=1 |
| _version_ | 1818651635751059456 |
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| author | Elham Shadmehr Nastaran Jenabi Dehkordi |
| author_facet | Elham Shadmehr Nastaran Jenabi Dehkordi |
| author_sort | Elham Shadmehr |
| collection | DOAJ |
| description | Background and Aim : Regenerative endodontics with the goal of replacing the lost dental tissues is developing fast. The aim of this study was to review the recent progressions, known limitations and advantages of regenerative treatments compared to other possible treatment modalities .
Materials and Methods : We searched MedLine and PubMed systematically for articles published from May 2000 until May 2013 in English which were relevant to tissue engineering and regenerative procedures using the keywords “cell and tissue based therapy”, “regeneration”, “stem cell” and “tissue engineering”. More valid papers were chosen .
Results : Stem cells, growth factors and an appropriate scaffold are the three essential elements required for tissue regeneration. Revascularization is an ideal regenerative treatment, which uses a fibrin scaffold. This scaffold is made of peri-radicular stem cells, a clot and latent growth factors in dentinal walls. The clinical outcome of revascularization is complete root formation in a premature necrotic permanent tooth. Thus, revascularization is a realistic and worthwhile approach in patients with fair to good prognosis .
Conclusion : Regenerative treatments with the aim of producing a completely formed permanent tooth are going to revolutionize dental science. Regeneration of a fully formed tooth is much more complicated than treatment of an open apex tooth and this issue requires further studies . |
| first_indexed | 2024-12-17T02:09:15Z |
| format | Article |
| id | doaj.art-f1e910e487e84e56a5b4c044683a8a6a |
| institution | Directory Open Access Journal |
| issn | 2383-3041 2383-3041 |
| language | English |
| last_indexed | 2024-12-17T02:09:15Z |
| publishDate | 2014-07-01 |
| publisher | Islamic Dental Association of Iran |
| record_format | Article |
| series | Journal of Islamic Dental Association of Iran |
| spelling | doaj.art-f1e910e487e84e56a5b4c044683a8a6a2022-12-21T22:07:37ZengIslamic Dental Association of IranJournal of Islamic Dental Association of Iran2383-30412383-30412014-07-01263197207A Review on Regenerative EndodonticsElham Shadmehr0Nastaran Jenabi Dehkordi1 Assistant Professor, Department of Endodontics, School of Dentistry, Isfahan University of Medical Sciences. Isfahan, Iran Student Dentistry, School of Dentistry, Isfahan University of Medical Sciences. Isfahan, Iran Background and Aim : Regenerative endodontics with the goal of replacing the lost dental tissues is developing fast. The aim of this study was to review the recent progressions, known limitations and advantages of regenerative treatments compared to other possible treatment modalities . Materials and Methods : We searched MedLine and PubMed systematically for articles published from May 2000 until May 2013 in English which were relevant to tissue engineering and regenerative procedures using the keywords “cell and tissue based therapy”, “regeneration”, “stem cell” and “tissue engineering”. More valid papers were chosen . Results : Stem cells, growth factors and an appropriate scaffold are the three essential elements required for tissue regeneration. Revascularization is an ideal regenerative treatment, which uses a fibrin scaffold. This scaffold is made of peri-radicular stem cells, a clot and latent growth factors in dentinal walls. The clinical outcome of revascularization is complete root formation in a premature necrotic permanent tooth. Thus, revascularization is a realistic and worthwhile approach in patients with fair to good prognosis . Conclusion : Regenerative treatments with the aim of producing a completely formed permanent tooth are going to revolutionize dental science. Regeneration of a fully formed tooth is much more complicated than treatment of an open apex tooth and this issue requires further studies .http://jidai.ir/browse.php?a_code=A-10-1-775&slc_lang=en&sid=1Cell and tissue-based therapyRegenerationStem cellTissue engineering |
| spellingShingle | Elham Shadmehr Nastaran Jenabi Dehkordi A Review on Regenerative Endodontics Journal of Islamic Dental Association of Iran Cell and tissue-based therapy Regeneration Stem cell Tissue engineering |
| title | A Review on Regenerative Endodontics |
| title_full | A Review on Regenerative Endodontics |
| title_fullStr | A Review on Regenerative Endodontics |
| title_full_unstemmed | A Review on Regenerative Endodontics |
| title_short | A Review on Regenerative Endodontics |
| title_sort | review on regenerative endodontics |
| topic | Cell and tissue-based therapy Regeneration Stem cell Tissue engineering |
| url | http://jidai.ir/browse.php?a_code=A-10-1-775&slc_lang=en&sid=1 |
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