Primary Nasopharngeal Yolk Sac Tumor: A Case Report
Yolk sac tumour also known as primitive endodermal tumour is the most common malignant germ cell tumour (GCT) in the paediatric age group. Most common sites of involvement are ovaries and testes, but rarely can occur in the extragonadal sites. In the head and neck region, yolk sac tumours have bee...
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JCDR Research and Publications Private Limited
2016-05-01
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| Series: | Journal of Clinical and Diagnostic Research |
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| Online Access: | https://jcdr.net/articles/PDF/7760/17620_CE(RA1)_F(T)_PF1(VSUAK)_PFA(AK)_PF2(PAG).pdf |
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| author | Dhanalakshmi Arumugam Pavithra Thandavarayan Lalitha Chidambaram Sudha Boj Sumathi Marudasalam |
| author_facet | Dhanalakshmi Arumugam Pavithra Thandavarayan Lalitha Chidambaram Sudha Boj Sumathi Marudasalam |
| author_sort | Dhanalakshmi Arumugam |
| collection | DOAJ |
| description | Yolk sac tumour also known as primitive endodermal tumour is the most common malignant germ cell tumour (GCT) in the paediatric
age group. Most common sites of involvement are ovaries and testes, but rarely can occur in the extragonadal sites. In the head and
neck region, yolk sac tumours have been reported in the nasopharynx, sinonasal tract, orbit, ear and parotid gland. Nasopharynx is
an uncommon site for yolk sac tumour and very few cases of nasopharngeal pure yolk sac tumour have been reported so far. Yolk sac
tumours are highly malignant and have a poor prognosis. This is a case of pure GCT in a three-year-old female child who presented with a
rapidly growing nasopharyngeal mass. Histopathological examination followed by immunohistochemistry and serum AFP study clinched
the diagnosis of yolk sac tumour. The tumour responded well to chemotherapy as evidenced by decrease in serum AFP levels. |
| first_indexed | 2024-12-22T04:25:19Z |
| format | Article |
| id | doaj.art-f1ecd1ed179d494b96b13f82507300bc |
| institution | Directory Open Access Journal |
| issn | 2249-782X 0973-709X |
| language | English |
| last_indexed | 2024-12-22T04:25:19Z |
| publishDate | 2016-05-01 |
| publisher | JCDR Research and Publications Private Limited |
| record_format | Article |
| series | Journal of Clinical and Diagnostic Research |
| spelling | doaj.art-f1ecd1ed179d494b96b13f82507300bc2022-12-21T18:39:10ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2016-05-01105ED06ED0710.7860/JCDR/2016/17620.7760Primary Nasopharngeal Yolk Sac Tumor: A Case ReportDhanalakshmi Arumugam0Pavithra Thandavarayan1Lalitha Chidambaram2Sudha Boj3Sumathi Marudasalam4Associate Professor, Department of Pathology, Coimbatore Medical College, Coimbatore, Tamil Nadu, India.Assistant Professor, Department of Pathology, Coimbatore Medical College, Coimbatore, Tamil Nadu, India.Professor, Department of Pathology, Coimbatore Medical College, Coimbatore, Tamil Nadu, India.Senior Assistant Professor, Department of Pathology, Coimbatore Medical College, Coimbatore, Tamil Nadu, India.Senior Assistant Professor, Department of Pathology, Coimbatore Medical College, Coimbatore, Tamil Nadu, India.Yolk sac tumour also known as primitive endodermal tumour is the most common malignant germ cell tumour (GCT) in the paediatric age group. Most common sites of involvement are ovaries and testes, but rarely can occur in the extragonadal sites. In the head and neck region, yolk sac tumours have been reported in the nasopharynx, sinonasal tract, orbit, ear and parotid gland. Nasopharynx is an uncommon site for yolk sac tumour and very few cases of nasopharngeal pure yolk sac tumour have been reported so far. Yolk sac tumours are highly malignant and have a poor prognosis. This is a case of pure GCT in a three-year-old female child who presented with a rapidly growing nasopharyngeal mass. Histopathological examination followed by immunohistochemistry and serum AFP study clinched the diagnosis of yolk sac tumour. The tumour responded well to chemotherapy as evidenced by decrease in serum AFP levels.https://jcdr.net/articles/PDF/7760/17620_CE(RA1)_F(T)_PF1(VSUAK)_PFA(AK)_PF2(PAG).pdfalpha- fetoproteingerm cell tumoursschiller –duval bodies |
| spellingShingle | Dhanalakshmi Arumugam Pavithra Thandavarayan Lalitha Chidambaram Sudha Boj Sumathi Marudasalam Primary Nasopharngeal Yolk Sac Tumor: A Case Report Journal of Clinical and Diagnostic Research alpha- fetoprotein germ cell tumours schiller –duval bodies |
| title | Primary Nasopharngeal Yolk Sac Tumor: A Case Report |
| title_full | Primary Nasopharngeal Yolk Sac Tumor: A Case Report |
| title_fullStr | Primary Nasopharngeal Yolk Sac Tumor: A Case Report |
| title_full_unstemmed | Primary Nasopharngeal Yolk Sac Tumor: A Case Report |
| title_short | Primary Nasopharngeal Yolk Sac Tumor: A Case Report |
| title_sort | primary nasopharngeal yolk sac tumor a case report |
| topic | alpha- fetoprotein germ cell tumours schiller –duval bodies |
| url | https://jcdr.net/articles/PDF/7760/17620_CE(RA1)_F(T)_PF1(VSUAK)_PFA(AK)_PF2(PAG).pdf |
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