Determination of anti-phage antibodies in calf sera following application of Escherichia coli and Mannheimia haemolytica-specific bacteriophages

The widespread occurrence of drug-resistant bacteria has increased interest in alternatives to antibiotics for combatting bacterial infections, among which bacteriophages play an important role. The ability of phage proteins to induce an anti-phage immune response can significantly limit the effecti...

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Main Authors: Urban-Chmiel Renata, Nowaczek Anna, Chmiel Paulina, Wawrzykowski Jacek, Pyzik Ewelina, Marek Agnieszka, Stępien-Pyśniak Dagmara, Alomari Mohammed M.M., Dec Marta
Format: Article
Language:English
Published: Sciendo 2022-08-01
Series:Journal of Veterinary Research
Subjects:
Online Access:https://doi.org/10.2478/jvetres-2022-0041
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author Urban-Chmiel Renata
Nowaczek Anna
Chmiel Paulina
Wawrzykowski Jacek
Pyzik Ewelina
Marek Agnieszka
Stępien-Pyśniak Dagmara
Alomari Mohammed M.M.
Dec Marta
author_facet Urban-Chmiel Renata
Nowaczek Anna
Chmiel Paulina
Wawrzykowski Jacek
Pyzik Ewelina
Marek Agnieszka
Stępien-Pyśniak Dagmara
Alomari Mohammed M.M.
Dec Marta
author_sort Urban-Chmiel Renata
collection DOAJ
description The widespread occurrence of drug-resistant bacteria has increased interest in alternatives to antibiotics for combatting bacterial infections, among which bacteriophages play an important role. The ability of phage proteins to induce an anti-phage immune response can significantly limit the effectiveness of treatment, which was the basis for the study described in this article. The aim of the study was to assess the effects of bacteriophages on the induction of an anti-phage humoral response in calves.
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spelling doaj.art-f1f2f8a25717439a83b768631d4f914c2023-05-06T15:31:52ZengSciendoJournal of Veterinary Research2450-86082022-08-0166335336010.2478/jvetres-2022-0041Determination of anti-phage antibodies in calf sera following application of Escherichia coli and Mannheimia haemolytica-specific bacteriophagesUrban-Chmiel Renata0Nowaczek Anna1Chmiel Paulina2Wawrzykowski Jacek3Pyzik Ewelina4Marek Agnieszka5Stępien-Pyśniak Dagmara6Alomari Mohammed M.M.7Dec Marta8Department of Veterinary Prevention and Avian Diseases, LublinPolandDepartment of Veterinary Prevention and Avian Diseases, LublinPolandChair and Department of Biology and Genetics, Medical University of Lublin, Lublin, 20-093, LublinPolandDepartment of Biochemistry, Faculty of Veterinary Medicine, University of Life Sciences in Lublin, 20-033Lublin, PolandDepartment of Veterinary Prevention and Avian Diseases, LublinPolandDepartment of Veterinary Prevention and Avian Diseases, LublinPolandDepartment of Veterinary Prevention and Avian Diseases, LublinPolandUniversity of Al Muthanna, Faculty of Veterinary Medicine, Al Muthanna66001, IraqDepartment of Veterinary Prevention and Avian Diseases, LublinPolandThe widespread occurrence of drug-resistant bacteria has increased interest in alternatives to antibiotics for combatting bacterial infections, among which bacteriophages play an important role. The ability of phage proteins to induce an anti-phage immune response can significantly limit the effectiveness of treatment, which was the basis for the study described in this article. The aim of the study was to assess the effects of bacteriophages on the induction of an anti-phage humoral response in calves.https://doi.org/10.2478/jvetres-2022-0041bacteriophagese. colielisam. haemolyticaimmunoglobulins
spellingShingle Urban-Chmiel Renata
Nowaczek Anna
Chmiel Paulina
Wawrzykowski Jacek
Pyzik Ewelina
Marek Agnieszka
Stępien-Pyśniak Dagmara
Alomari Mohammed M.M.
Dec Marta
Determination of anti-phage antibodies in calf sera following application of Escherichia coli and Mannheimia haemolytica-specific bacteriophages
Journal of Veterinary Research
bacteriophages
e. coli
elisa
m. haemolytica
immunoglobulins
title Determination of anti-phage antibodies in calf sera following application of Escherichia coli and Mannheimia haemolytica-specific bacteriophages
title_full Determination of anti-phage antibodies in calf sera following application of Escherichia coli and Mannheimia haemolytica-specific bacteriophages
title_fullStr Determination of anti-phage antibodies in calf sera following application of Escherichia coli and Mannheimia haemolytica-specific bacteriophages
title_full_unstemmed Determination of anti-phage antibodies in calf sera following application of Escherichia coli and Mannheimia haemolytica-specific bacteriophages
title_short Determination of anti-phage antibodies in calf sera following application of Escherichia coli and Mannheimia haemolytica-specific bacteriophages
title_sort determination of anti phage antibodies in calf sera following application of escherichia coli and mannheimia haemolytica specific bacteriophages
topic bacteriophages
e. coli
elisa
m. haemolytica
immunoglobulins
url https://doi.org/10.2478/jvetres-2022-0041
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