Spectral fingerprints or spectral tilt? Evidence for distinct oscillatory signatures of memory formation.
Decreases in low-frequency power (2-30 Hz) alongside high-frequency power increases (>40 Hz) have been demonstrated to predict successful memory formation. Parsimoniously, this change in the frequency spectrum can be explained by one factor, a change in the tilt of the power spectrum (from steep...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2019-07-01
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| Series: | PLoS Biology |
| Online Access: | https://doi.org/10.1371/journal.pbio.3000403 |
| _version_ | 1819031424440729600 |
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| author | Marie-Christin Fellner Stephanie Gollwitzer Stefan Rampp Gernot Kreiselmeyr Daniel Bush Beate Diehl Nikolai Axmacher Hajo Hamer Simon Hanslmayr |
| author_facet | Marie-Christin Fellner Stephanie Gollwitzer Stefan Rampp Gernot Kreiselmeyr Daniel Bush Beate Diehl Nikolai Axmacher Hajo Hamer Simon Hanslmayr |
| author_sort | Marie-Christin Fellner |
| collection | DOAJ |
| description | Decreases in low-frequency power (2-30 Hz) alongside high-frequency power increases (>40 Hz) have been demonstrated to predict successful memory formation. Parsimoniously, this change in the frequency spectrum can be explained by one factor, a change in the tilt of the power spectrum (from steep to flat) indicating engaged brain regions. A competing view is that the change in the power spectrum contains several distinct brain oscillatory fingerprints, each serving different computations. Here, we contrast these two theories in a parallel magnetoencephalography (MEG)-intracranial electroencephalography (iEEG) study in which healthy participants and epilepsy patients, respectively, studied either familiar verbal material or unfamiliar faces. We investigated whether modulations in specific frequency bands can be dissociated in time and space and by experimental manipulation. Both MEG and iEEG data show that decreases in alpha/beta power specifically predicted the encoding of words but not faces, whereas increases in gamma power and decreases in theta power predicted memory formation irrespective of material. Critically, these different oscillatory signatures of memory encoding were evident in different brain regions. Moreover, high-frequency gamma power increases occurred significantly earlier compared to low-frequency theta power decreases. These results show that simple "spectral tilt" cannot explain common oscillatory changes and demonstrate that brain oscillations in different frequency bands serve different functions for memory encoding. |
| first_indexed | 2024-12-21T06:45:50Z |
| format | Article |
| id | doaj.art-f1f2fd0ae25f41f1b752a10299f570f3 |
| institution | Directory Open Access Journal |
| issn | 1544-9173 1545-7885 |
| language | English |
| last_indexed | 2024-12-21T06:45:50Z |
| publishDate | 2019-07-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS Biology |
| spelling | doaj.art-f1f2fd0ae25f41f1b752a10299f570f32022-12-21T19:12:37ZengPublic Library of Science (PLoS)PLoS Biology1544-91731545-78852019-07-01177e300040310.1371/journal.pbio.3000403Spectral fingerprints or spectral tilt? Evidence for distinct oscillatory signatures of memory formation.Marie-Christin FellnerStephanie GollwitzerStefan RamppGernot KreiselmeyrDaniel BushBeate DiehlNikolai AxmacherHajo HamerSimon HanslmayrDecreases in low-frequency power (2-30 Hz) alongside high-frequency power increases (>40 Hz) have been demonstrated to predict successful memory formation. Parsimoniously, this change in the frequency spectrum can be explained by one factor, a change in the tilt of the power spectrum (from steep to flat) indicating engaged brain regions. A competing view is that the change in the power spectrum contains several distinct brain oscillatory fingerprints, each serving different computations. Here, we contrast these two theories in a parallel magnetoencephalography (MEG)-intracranial electroencephalography (iEEG) study in which healthy participants and epilepsy patients, respectively, studied either familiar verbal material or unfamiliar faces. We investigated whether modulations in specific frequency bands can be dissociated in time and space and by experimental manipulation. Both MEG and iEEG data show that decreases in alpha/beta power specifically predicted the encoding of words but not faces, whereas increases in gamma power and decreases in theta power predicted memory formation irrespective of material. Critically, these different oscillatory signatures of memory encoding were evident in different brain regions. Moreover, high-frequency gamma power increases occurred significantly earlier compared to low-frequency theta power decreases. These results show that simple "spectral tilt" cannot explain common oscillatory changes and demonstrate that brain oscillations in different frequency bands serve different functions for memory encoding.https://doi.org/10.1371/journal.pbio.3000403 |
| spellingShingle | Marie-Christin Fellner Stephanie Gollwitzer Stefan Rampp Gernot Kreiselmeyr Daniel Bush Beate Diehl Nikolai Axmacher Hajo Hamer Simon Hanslmayr Spectral fingerprints or spectral tilt? Evidence for distinct oscillatory signatures of memory formation. PLoS Biology |
| title | Spectral fingerprints or spectral tilt? Evidence for distinct oscillatory signatures of memory formation. |
| title_full | Spectral fingerprints or spectral tilt? Evidence for distinct oscillatory signatures of memory formation. |
| title_fullStr | Spectral fingerprints or spectral tilt? Evidence for distinct oscillatory signatures of memory formation. |
| title_full_unstemmed | Spectral fingerprints or spectral tilt? Evidence for distinct oscillatory signatures of memory formation. |
| title_short | Spectral fingerprints or spectral tilt? Evidence for distinct oscillatory signatures of memory formation. |
| title_sort | spectral fingerprints or spectral tilt evidence for distinct oscillatory signatures of memory formation |
| url | https://doi.org/10.1371/journal.pbio.3000403 |
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