In vitro evaluation of probiotic properties and antioxidant activities of Bifidobacterium strains from infant feces in the Uyghur population of northwestern China
Abstract Purpose Bifidobacterium is an important probiotic used in food and medicine production. The probiotic properties of bifidobacteria are strain specific, so it is necessary to evaluate the probiotic properties of bifidobacteria isolated from specific populations, especially when developing pr...
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| Format: | Article |
| Language: | English |
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BMC
2022-04-01
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| Series: | Annals of Microbiology |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13213-022-01670-y |
| _version_ | 1811291112876277760 |
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| author | Jingjing Cai Ji Bai Baolong Luo Yongqing Ni Fengwei Tian Wenli Yan |
| author_facet | Jingjing Cai Ji Bai Baolong Luo Yongqing Ni Fengwei Tian Wenli Yan |
| author_sort | Jingjing Cai |
| collection | DOAJ |
| description | Abstract Purpose Bifidobacterium is an important probiotic used in food and medicine production. The probiotic properties of bifidobacteria are strain specific, so it is necessary to evaluate the probiotic properties of bifidobacteria isolated from specific populations, especially when developing products suitable for specific populations. The objective of this study was to evaluate the probiotic potential and safety of bifidobacteria isolated from healthy Uyghur infants from northwestern China. Methods In this study, antimicrobial activity, antibiotic sensitivity, hemolytic, acid and bile tolerance, hydrophobicity, co-aggregation, auto-aggregation, and antioxidant activity were evaluated. Results Based on antagonistic activity spectrum against seven intestinal pathogenic bacteria, 14 excellent strains were initially selected. Among 14 strains, four bifidobacteria strains (BF17-4, BF52-1, BF87-3, and BF88-5) were superior to strain Lactobacillus rhamnosus GG in cell surface hydrophobicity and auto-aggregation percentages and close to strain GG in co-aggregation with Escherichia coli EPEC O127: K63 (CICC 10411). The antioxidant activities of each of the 14 bifidobacteria strains varied with the cell components. Most of the strains were sensitive to all the antimicrobials tested, except kanamycin and amikacin. Conclusion BF17-4 and BF52-1 are good candidates for further in vivo studies and further used in functional foods. |
| first_indexed | 2024-04-13T04:23:36Z |
| format | Article |
| id | doaj.art-f1f490dc86e84c7bad33b6b89c5d22ad |
| institution | Directory Open Access Journal |
| issn | 1590-4261 1869-2044 |
| language | English |
| last_indexed | 2024-04-13T04:23:36Z |
| publishDate | 2022-04-01 |
| publisher | BMC |
| record_format | Article |
| series | Annals of Microbiology |
| spelling | doaj.art-f1f490dc86e84c7bad33b6b89c5d22ad2022-12-22T03:02:38ZengBMCAnnals of Microbiology1590-42611869-20442022-04-0172111410.1186/s13213-022-01670-yIn vitro evaluation of probiotic properties and antioxidant activities of Bifidobacterium strains from infant feces in the Uyghur population of northwestern ChinaJingjing Cai0Ji Bai1Baolong Luo2Yongqing Ni3Fengwei Tian4Wenli Yan5The Food College of Shihezi UniversityThe Food College of Shihezi UniversityThe Food College of Shihezi UniversityThe Food College of Shihezi UniversitySchool of Food Science and Technology, Jiangnan UniversityThe Food College of Shihezi UniversityAbstract Purpose Bifidobacterium is an important probiotic used in food and medicine production. The probiotic properties of bifidobacteria are strain specific, so it is necessary to evaluate the probiotic properties of bifidobacteria isolated from specific populations, especially when developing products suitable for specific populations. The objective of this study was to evaluate the probiotic potential and safety of bifidobacteria isolated from healthy Uyghur infants from northwestern China. Methods In this study, antimicrobial activity, antibiotic sensitivity, hemolytic, acid and bile tolerance, hydrophobicity, co-aggregation, auto-aggregation, and antioxidant activity were evaluated. Results Based on antagonistic activity spectrum against seven intestinal pathogenic bacteria, 14 excellent strains were initially selected. Among 14 strains, four bifidobacteria strains (BF17-4, BF52-1, BF87-3, and BF88-5) were superior to strain Lactobacillus rhamnosus GG in cell surface hydrophobicity and auto-aggregation percentages and close to strain GG in co-aggregation with Escherichia coli EPEC O127: K63 (CICC 10411). The antioxidant activities of each of the 14 bifidobacteria strains varied with the cell components. Most of the strains were sensitive to all the antimicrobials tested, except kanamycin and amikacin. Conclusion BF17-4 and BF52-1 are good candidates for further in vivo studies and further used in functional foods.https://doi.org/10.1186/s13213-022-01670-yBifidobacteriumProbiotic propertiesAntioxidant activitiesInfant intestines |
| spellingShingle | Jingjing Cai Ji Bai Baolong Luo Yongqing Ni Fengwei Tian Wenli Yan In vitro evaluation of probiotic properties and antioxidant activities of Bifidobacterium strains from infant feces in the Uyghur population of northwestern China Annals of Microbiology Bifidobacterium Probiotic properties Antioxidant activities Infant intestines |
| title | In vitro evaluation of probiotic properties and antioxidant activities of Bifidobacterium strains from infant feces in the Uyghur population of northwestern China |
| title_full | In vitro evaluation of probiotic properties and antioxidant activities of Bifidobacterium strains from infant feces in the Uyghur population of northwestern China |
| title_fullStr | In vitro evaluation of probiotic properties and antioxidant activities of Bifidobacterium strains from infant feces in the Uyghur population of northwestern China |
| title_full_unstemmed | In vitro evaluation of probiotic properties and antioxidant activities of Bifidobacterium strains from infant feces in the Uyghur population of northwestern China |
| title_short | In vitro evaluation of probiotic properties and antioxidant activities of Bifidobacterium strains from infant feces in the Uyghur population of northwestern China |
| title_sort | in vitro evaluation of probiotic properties and antioxidant activities of bifidobacterium strains from infant feces in the uyghur population of northwestern china |
| topic | Bifidobacterium Probiotic properties Antioxidant activities Infant intestines |
| url | https://doi.org/10.1186/s13213-022-01670-y |
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