Mitochondrion-targeted antioxidant SkQ1 prevents rapid animal death caused by highly diverse shocks

Abstract The response to stress involves the activation of pathways leading either to protection from the stress origin, eventually resulting in development of stress resistance, or activation of the rapid death of the organism. Here we hypothesize that mitochondrial reactive oxygen species (mtROS)...

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Bibliographic Details
Main Authors: V. P. Skulachev, M. Yu. Vyssokikh, B. V. Chernyak, O. A. Averina, A. A. Andreev-Andrievskiy, R. A. Zinovkin, K. G. Lyamzaev, M. V. Marey, M. V. Egorov, O. J. Frolova, D. B. Zorov, M. V. Skulachev, V. A. Sadovnichii
Format: Article
Language:English
Published: Nature Portfolio 2023-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-31281-9