Exploitation of Antimicrobial Nanoparticles and Their Applications in Biomedical Engineering
Antibiotic resistance is a major threat to public health, which contributes largely to increased mortality rates and costs in hospitals. The severity and widespread nature of antibiotic resistance result in limited treatments to effectively combat antibiotic-resistant pathogens. Nanoparticles have d...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-05-01
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| Series: | Applied Sciences |
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| Online Access: | https://www.mdpi.com/2076-3417/11/10/4520 |
| _version_ | 1797533987406610432 |
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| author | XiuYi Yang Etelka Chung Ian Johnston Guogang Ren Yuen-Ki Cheong |
| author_facet | XiuYi Yang Etelka Chung Ian Johnston Guogang Ren Yuen-Ki Cheong |
| author_sort | XiuYi Yang |
| collection | DOAJ |
| description | Antibiotic resistance is a major threat to public health, which contributes largely to increased mortality rates and costs in hospitals. The severity and widespread nature of antibiotic resistance result in limited treatments to effectively combat antibiotic-resistant pathogens. Nanoparticles have different or enhanced properties in contrast to their bulk material, including antimicrobial efficacy towards a broad range of microorganisms. Their beneficial properties can be utilised in various bioengineering technologies. Thus, antimicrobial nanoparticles may provide an alternative to challenge antibiotic resistance. Currently, nanoparticles have been incorporated into materials, such as fibres, glass and paints. However, more research is required to elucidate the mechanisms of action fully and to advance biomedical applications further. This paper reviews the antimicrobial efficacies and the intrinsic properties of different metallic nanoparticles, their potential mechanisms of action against certain types of harmful pathogens and how these properties may be utilised in biomedical and healthcare products with the aim to reduce cross contaminations, disease transmissions and usage of antibiotics. |
| first_indexed | 2024-03-10T11:23:28Z |
| format | Article |
| id | doaj.art-f1f69f96103f44d5a0371be7efb29939 |
| institution | Directory Open Access Journal |
| issn | 2076-3417 |
| language | English |
| last_indexed | 2024-03-10T11:23:28Z |
| publishDate | 2021-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Applied Sciences |
| spelling | doaj.art-f1f69f96103f44d5a0371be7efb299392023-11-21T19:55:14ZengMDPI AGApplied Sciences2076-34172021-05-011110452010.3390/app11104520Exploitation of Antimicrobial Nanoparticles and Their Applications in Biomedical EngineeringXiuYi Yang0Etelka Chung1Ian Johnston2Guogang Ren3Yuen-Ki Cheong4School of Physics, Engineering and Computer Science, University of Hertfordshire, Hatfield AL10 9AB, UKSchool of Physics, Engineering and Computer Science, University of Hertfordshire, Hatfield AL10 9AB, UKSchool of Physics, Engineering and Computer Science, University of Hertfordshire, Hatfield AL10 9AB, UKSchool of Physics, Engineering and Computer Science, University of Hertfordshire, Hatfield AL10 9AB, UKSchool of Physics, Engineering and Computer Science, University of Hertfordshire, Hatfield AL10 9AB, UKAntibiotic resistance is a major threat to public health, which contributes largely to increased mortality rates and costs in hospitals. The severity and widespread nature of antibiotic resistance result in limited treatments to effectively combat antibiotic-resistant pathogens. Nanoparticles have different or enhanced properties in contrast to their bulk material, including antimicrobial efficacy towards a broad range of microorganisms. Their beneficial properties can be utilised in various bioengineering technologies. Thus, antimicrobial nanoparticles may provide an alternative to challenge antibiotic resistance. Currently, nanoparticles have been incorporated into materials, such as fibres, glass and paints. However, more research is required to elucidate the mechanisms of action fully and to advance biomedical applications further. This paper reviews the antimicrobial efficacies and the intrinsic properties of different metallic nanoparticles, their potential mechanisms of action against certain types of harmful pathogens and how these properties may be utilised in biomedical and healthcare products with the aim to reduce cross contaminations, disease transmissions and usage of antibiotics.https://www.mdpi.com/2076-3417/11/10/4520antimicrobialantibacterialantifungalnanomaterialnanoparticlebottom-up |
| spellingShingle | XiuYi Yang Etelka Chung Ian Johnston Guogang Ren Yuen-Ki Cheong Exploitation of Antimicrobial Nanoparticles and Their Applications in Biomedical Engineering Applied Sciences antimicrobial antibacterial antifungal nanomaterial nanoparticle bottom-up |
| title | Exploitation of Antimicrobial Nanoparticles and Their Applications in Biomedical Engineering |
| title_full | Exploitation of Antimicrobial Nanoparticles and Their Applications in Biomedical Engineering |
| title_fullStr | Exploitation of Antimicrobial Nanoparticles and Their Applications in Biomedical Engineering |
| title_full_unstemmed | Exploitation of Antimicrobial Nanoparticles and Their Applications in Biomedical Engineering |
| title_short | Exploitation of Antimicrobial Nanoparticles and Their Applications in Biomedical Engineering |
| title_sort | exploitation of antimicrobial nanoparticles and their applications in biomedical engineering |
| topic | antimicrobial antibacterial antifungal nanomaterial nanoparticle bottom-up |
| url | https://www.mdpi.com/2076-3417/11/10/4520 |
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