Dual role of peripheral B cells in multiple sclerosis: emerging remote players in demyelination and novel diagnostic biomarkers

Dual role of peripheral B cells in multiple sclerosis: emerging remote players in demyelination and novel diagnostic biomarkers

IntroductionMultiple sclerosis is an inflammatory and demyelinating disease caused by a pathogenic immune response against the myelin sheath surfaces of oligodendrocytes. The demyelination has been classically associated with pathogenic B cells residing in the central nervous system that release aut...

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Bibliographic Details
Main Authors: Gabriel Torres Iglesias, Mireya Fernández-Fournier, MariPaz López-Molina, Dolores Piniella, Fernando Laso-García, Mari Carmen Gómez-de Frutos, Elisa Alonso-López, Lucía Botella, Beatriz Chamorro, Sara Sánchez-Velasco, Inmaculada Puertas, Antonio Tallón Barranco, Pilar Nozal, Exuperio Díez-Tejedor, María Gutiérrez-Fernández, Laura Otero-Ortega
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-08-01
Series:Frontiers in Immunology
Subjects:
demyelination
serum diagnostic biomarkers
extracellular vesicles
multiple sclerosis
myelin antibodies
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1224217/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1224217/full

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