Induced pluripotent stem cells modulate the Wnt pathway in the bleomycin-induced model of idiopathic pulmonary fibrosis

Induced pluripotent stem cells modulate the Wnt pathway in the bleomycin-induced model of idiopathic pulmonary fibrosis

Abstract Background The Wnt signaling pathway has been implicated in the pathogenesis of fibrotic disorders and malignancies. Hence, we aimed to assess the potential of the induced pluripotent stem cells (IPS) in modulating the expression of the cardinal genes of the Wnt pathway in a mouse model of...

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Bibliographic Details
Main Authors: Paria Bayati, Marjan Taherian, Mansoureh Soleimani, Hamid Farajifard, Nazanin Mojtabavi
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Stem Cell Research & Therapy
Subjects:
WNT
b-Catenin
BMP4
DKK1
IPF
IPSC
Online Access:https://doi.org/10.1186/s13287-023-03581-4

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