Effect of quercetin on the pharmacokinetics of selexipag and its active metabolite in beagles

Effect of quercetin on the pharmacokinetics of selexipag and its active metabolite in beagles

Context As an inhibitor cytochrome P450 family 2 subfamily C polypeptide 8 (CYP2C8), quercetin is a naturally occurring flavonoid with its glycosides consumed at least 100 mg per day in food. However, it is still unknown whether quercetin and selexipag interact. Objective The study investigated the...

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Bibliographic Details
Main Authors:	Shun-bin Luo, Er-min Gu, Yu-ao Chen, Shi-chen Zhou, Chen Fan, Ren-ai Xu
Format:	Article
Language:	English
Published:	Taylor & Francis Group 2022-01-01
Series:	Pharmaceutical Biology
Subjects:	cyp2c8 act-333679 uplc-ms/ms inhibit metabolism
Online Access:	http://dx.doi.org/10.1080/13880209.2021.2005636

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