Drug-induced liver injuries in pregnancy in the context of polypragmasy
Pregnancy is characterized by overexertion of metabolism in the liver and some changes in metabolism, which can lead to various, including severe organ, damage. During pregnancy, according to international epidemiological studies, more than 80 % of women take medicines. Under polypragmasy it is extr...
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Format: | Article |
Language: | Russian |
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Ministry of Health of the Russian Federation, Federal State Budgetary Institution «Scientific Centre for Expert Evaluation of Medicinal Products»
2018-02-01
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Series: | Безопасность и риск фармакотерапии |
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Online Access: | https://www.risksafety.ru/jour/article/view/78 |
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author | N. Yu. Velts E. O. Zhuravleva M. A. Darmostukova K. E. Zatolochina O. S. Alyautdina |
author_facet | N. Yu. Velts E. O. Zhuravleva M. A. Darmostukova K. E. Zatolochina O. S. Alyautdina |
author_sort | N. Yu. Velts |
collection | DOAJ |
description | Pregnancy is characterized by overexertion of metabolism in the liver and some changes in metabolism, which can lead to various, including severe organ, damage. During pregnancy, according to international epidemiological studies, more than 80 % of women take medicines. Under polypragmasy it is extremely difficult to isolate a particular medicine responsible for the drug pathology in the liver in pregnant women. The article presents a retrospective analysis of spontaneous reports accepted from the Russian database of AIS Roszdravnadzor for the period from 01.01.2009 to 31.12.2016. |
first_indexed | 2024-03-08T22:27:54Z |
format | Article |
id | doaj.art-f1fc43d4f2fc4eb39a8e1bd2a3bc40dd |
institution | Directory Open Access Journal |
issn | 2312-7821 2619-1164 |
language | Russian |
last_indexed | 2024-04-24T13:56:19Z |
publishDate | 2018-02-01 |
publisher | Ministry of Health of the Russian Federation, Federal State Budgetary Institution «Scientific Centre for Expert Evaluation of Medicinal Products» |
record_format | Article |
series | Безопасность и риск фармакотерапии |
spelling | doaj.art-f1fc43d4f2fc4eb39a8e1bd2a3bc40dd2024-04-03T17:56:36ZrusMinistry of Health of the Russian Federation, Federal State Budgetary Institution «Scientific Centre for Expert Evaluation of Medicinal Products»Безопасность и риск фармакотерапии2312-78212619-11642018-02-015310411178Drug-induced liver injuries in pregnancy in the context of polypragmasyN. Yu. Velts0E. O. Zhuravleva1M. A. Darmostukova2K. E. Zatolochina3O. S. Alyautdina4Scientific Centre for Expert Evaluation of Medicinal ProductsScientific Centre for Expert Evaluation of Medicinal ProductsScientific Centre for Expert Evaluation of Medicinal ProductsScientific Centre for Expert Evaluation of Medicinal ProductsI. M. Sechenov First Moscow State Medical UniversityPregnancy is characterized by overexertion of metabolism in the liver and some changes in metabolism, which can lead to various, including severe organ, damage. During pregnancy, according to international epidemiological studies, more than 80 % of women take medicines. Under polypragmasy it is extremely difficult to isolate a particular medicine responsible for the drug pathology in the liver in pregnant women. The article presents a retrospective analysis of spontaneous reports accepted from the Russian database of AIS Roszdravnadzor for the period from 01.01.2009 to 31.12.2016.https://www.risksafety.ru/jour/article/view/78беременностьлекарственный гепатитполивитаминыгестагеныспонтанные сообщенияроссийская база аис росздравнадзор «фармаконадзор»безопасность лекарственных средствpregnancydrug-induced hepatitismultivitaminsgestagensspontaneous reportsrussian ais database roszdravnadzor pharmacovigilancedrug safety |
spellingShingle | N. Yu. Velts E. O. Zhuravleva M. A. Darmostukova K. E. Zatolochina O. S. Alyautdina Drug-induced liver injuries in pregnancy in the context of polypragmasy Безопасность и риск фармакотерапии беременность лекарственный гепатит поливитамины гестагены спонтанные сообщения российская база аис росздравнадзор «фармаконадзор» безопасность лекарственных средств pregnancy drug-induced hepatitis multivitamins gestagens spontaneous reports russian ais database roszdravnadzor pharmacovigilance drug safety |
title | Drug-induced liver injuries in pregnancy in the context of polypragmasy |
title_full | Drug-induced liver injuries in pregnancy in the context of polypragmasy |
title_fullStr | Drug-induced liver injuries in pregnancy in the context of polypragmasy |
title_full_unstemmed | Drug-induced liver injuries in pregnancy in the context of polypragmasy |
title_short | Drug-induced liver injuries in pregnancy in the context of polypragmasy |
title_sort | drug induced liver injuries in pregnancy in the context of polypragmasy |
topic | беременность лекарственный гепатит поливитамины гестагены спонтанные сообщения российская база аис росздравнадзор «фармаконадзор» безопасность лекарственных средств pregnancy drug-induced hepatitis multivitamins gestagens spontaneous reports russian ais database roszdravnadzor pharmacovigilance drug safety |
url | https://www.risksafety.ru/jour/article/view/78 |
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