Recent Advances in Multifunctional Microneedle Patches for Wound Healing and Health Monitoring
Benefiting from the advantages of minimal invasiveness, painlessness, and ease to use, microneedle patches (MPs) have been extensively studied in the biomedical field through a physical penetration enhancement pathway. This study systematically summarizes the preparation methods, function optimizati...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley-VCH
2023-02-01
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| Series: | Advanced NanoBiomed Research |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/anbr.202200126 |
| _version_ | 1811169460256505856 |
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| author | Panpan Pan Qing Liu Lin Wang Chunxiao Wang Le Hu Yongjian Jiang Yonghui Deng Guisheng Li Jingdi Chen |
| author_facet | Panpan Pan Qing Liu Lin Wang Chunxiao Wang Le Hu Yongjian Jiang Yonghui Deng Guisheng Li Jingdi Chen |
| author_sort | Panpan Pan |
| collection | DOAJ |
| description | Benefiting from the advantages of minimal invasiveness, painlessness, and ease to use, microneedle patches (MPs) have been extensively studied in the biomedical field through a physical penetration enhancement pathway. This study systematically summarizes the preparation methods, function optimization, and diagnostic and therapeutic applications of MPs. First of all, the raw materials and methods commonly used in different preparation processes for MPs are highlighted. Then, the corresponding solutions to the problems facing MPs, such as poor tissue adhesion, weak mechanical strength, and low drug delivery utilization in their development and application, are emphasized, which serve as approaches to improve the performance of MPs. Subsequently, the latest applications of MPs for wound healing and health monitoring in recent years are summarized in‐depth, revealing the unique merits of MPs in diagnosis and treatment. Finally, the key points for the urgent improvement of MPs in clinical translation and commercial application are deliberated, in order to inspire the future direction of multifunctional and intelligent MPs. |
| first_indexed | 2024-04-10T16:43:52Z |
| format | Article |
| id | doaj.art-f1fce41ee7524c87925a8c8bbcf90f54 |
| institution | Directory Open Access Journal |
| issn | 2699-9307 |
| language | English |
| last_indexed | 2024-04-10T16:43:52Z |
| publishDate | 2023-02-01 |
| publisher | Wiley-VCH |
| record_format | Article |
| series | Advanced NanoBiomed Research |
| spelling | doaj.art-f1fce41ee7524c87925a8c8bbcf90f542023-02-08T05:18:55ZengWiley-VCHAdvanced NanoBiomed Research2699-93072023-02-0132n/an/a10.1002/anbr.202200126Recent Advances in Multifunctional Microneedle Patches for Wound Healing and Health MonitoringPanpan Pan0Qing Liu1Lin Wang2Chunxiao Wang3Le Hu4Yongjian Jiang5Yonghui Deng6Guisheng Li7Jingdi Chen8Marine College Shandong University Weihai 264209 ChinaMarine College Shandong University Weihai 264209 ChinaMarine College Shandong University Weihai 264209 ChinaMarine College Shandong University Weihai 264209 ChinaMarine College Shandong University Weihai 264209 ChinaDepartment of Pancreatic Surgery, Nephrology and Radiology Huashan Hospital Fudan University Shanghai 200040 ChinaDepartment of Chemistry Department of Gastroenterology Zhongshan Hospital of Fudan University, State Key Laboratory of Molecular Engineering of Polymers Collaborative Innovation Center of Chemistry for Energy Materials (iChEM) Fudan University Shanghai 200433 ChinaSchool of Materials and Chemistry University of Shanghai for Science and Technology Shanghai 200093 ChinaMarine College Shandong University Weihai 264209 ChinaBenefiting from the advantages of minimal invasiveness, painlessness, and ease to use, microneedle patches (MPs) have been extensively studied in the biomedical field through a physical penetration enhancement pathway. This study systematically summarizes the preparation methods, function optimization, and diagnostic and therapeutic applications of MPs. First of all, the raw materials and methods commonly used in different preparation processes for MPs are highlighted. Then, the corresponding solutions to the problems facing MPs, such as poor tissue adhesion, weak mechanical strength, and low drug delivery utilization in their development and application, are emphasized, which serve as approaches to improve the performance of MPs. Subsequently, the latest applications of MPs for wound healing and health monitoring in recent years are summarized in‐depth, revealing the unique merits of MPs in diagnosis and treatment. Finally, the key points for the urgent improvement of MPs in clinical translation and commercial application are deliberated, in order to inspire the future direction of multifunctional and intelligent MPs.https://doi.org/10.1002/anbr.202200126health monitoringmicroneedle patchesperformance optimizationphysical penetrationwound healing |
| spellingShingle | Panpan Pan Qing Liu Lin Wang Chunxiao Wang Le Hu Yongjian Jiang Yonghui Deng Guisheng Li Jingdi Chen Recent Advances in Multifunctional Microneedle Patches for Wound Healing and Health Monitoring Advanced NanoBiomed Research health monitoring microneedle patches performance optimization physical penetration wound healing |
| title | Recent Advances in Multifunctional Microneedle Patches for Wound Healing and Health Monitoring |
| title_full | Recent Advances in Multifunctional Microneedle Patches for Wound Healing and Health Monitoring |
| title_fullStr | Recent Advances in Multifunctional Microneedle Patches for Wound Healing and Health Monitoring |
| title_full_unstemmed | Recent Advances in Multifunctional Microneedle Patches for Wound Healing and Health Monitoring |
| title_short | Recent Advances in Multifunctional Microneedle Patches for Wound Healing and Health Monitoring |
| title_sort | recent advances in multifunctional microneedle patches for wound healing and health monitoring |
| topic | health monitoring microneedle patches performance optimization physical penetration wound healing |
| url | https://doi.org/10.1002/anbr.202200126 |
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