HAP1, a new revolutionary cell model for gene editing using CRISPR-Cas9

HAP1, a new revolutionary cell model for gene editing using CRISPR-Cas9

The use of next-generation sequencing (NGS) technologies has been instrumental in the characterization of the mutational landscape of complex human diseases like cancer. But despite the enormous rise in the identification of disease candidate genetic variants, their functionality is yet to be fully...

Full description

Bibliographic Details
Main Authors: Gemma Llargués-Sistac, Laia Bonjoch, Sergi Castellvi-Bel
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
HAP1
CRISPR-cas9
genome-engineering
functional validation
haploidy
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2023.1111488/full

Similar Items

Similar Items