Malignant sacro-coccygeal teratoma with growing teratoma syndrome
A 13-month-old female with sacro-coccygeal tumor type II by Altman, was proven by biopsy to be a malignant germ cell tumor. Serum tumor markers were normal. During neo-adjuvant chemotherapy visible tumor progression was confirmed radiologically and progressed despite changing chemotherapy. The exter...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2019-07-01
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| Series: | Journal of Pediatric Surgery Case Reports |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2213576618303464 |
| _version_ | 1830511999518244864 |
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| author | Tamador Al-Shamaileh Fatena Ajlouni Rasha Deebajah Iyad Sultan Mohammad M. Saleem Khalil Ghandour |
| author_facet | Tamador Al-Shamaileh Fatena Ajlouni Rasha Deebajah Iyad Sultan Mohammad M. Saleem Khalil Ghandour |
| author_sort | Tamador Al-Shamaileh |
| collection | DOAJ |
| description | A 13-month-old female with sacro-coccygeal tumor type II by Altman, was proven by biopsy to be a malignant germ cell tumor. Serum tumor markers were normal. During neo-adjuvant chemotherapy visible tumor progression was confirmed radiologically and progressed despite changing chemotherapy. The external growing mass forced its way out of the skin. More importantly, CT showed resolution of the pelvic component. Complete tumor resection with coccygectomy was performed. Histopathology showed mature teratoma, immature cells in the coccyx and no malignant germ cells. Three months after ending her therapy she remains in remission. We report the first case of growing teratoma syndrome (GTS) in the coccygeal region. Keywords: Sacro-coccygeal teratoma, Growing teratoma syndrome |
| first_indexed | 2024-12-22T02:20:19Z |
| format | Article |
| id | doaj.art-f201908a3de549dfa55b889f343e37c8 |
| institution | Directory Open Access Journal |
| issn | 2213-5766 |
| language | English |
| last_indexed | 2024-12-22T02:20:19Z |
| publishDate | 2019-07-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Pediatric Surgery Case Reports |
| spelling | doaj.art-f201908a3de549dfa55b889f343e37c82022-12-21T18:42:09ZengElsevierJournal of Pediatric Surgery Case Reports2213-57662019-07-0146Malignant sacro-coccygeal teratoma with growing teratoma syndromeTamador Al-Shamaileh0Fatena Ajlouni1Rasha Deebajah2Iyad Sultan3Mohammad M. Saleem4Khalil Ghandour5Pediatric Surgery Department, King Hussein Cancer Center, Amman, Jordan; Corresponding author. General Surgery Specialist, King Hussein Cancer Center-Pediatric Surgery Department Jordan.Radiology Department, King Hussein Cancer Center, Amman, JordanPediatric Oncology Department, King Hussein Cancer Center, Amman, JordanPediatric Oncology Department, King Hussein Cancer Center, Amman, JordanPediatric Surgery Department, King Hussein Cancer Center, Amman, JordanPediatric Surgery Department, King Hussein Cancer Center, Amman, JordanA 13-month-old female with sacro-coccygeal tumor type II by Altman, was proven by biopsy to be a malignant germ cell tumor. Serum tumor markers were normal. During neo-adjuvant chemotherapy visible tumor progression was confirmed radiologically and progressed despite changing chemotherapy. The external growing mass forced its way out of the skin. More importantly, CT showed resolution of the pelvic component. Complete tumor resection with coccygectomy was performed. Histopathology showed mature teratoma, immature cells in the coccyx and no malignant germ cells. Three months after ending her therapy she remains in remission. We report the first case of growing teratoma syndrome (GTS) in the coccygeal region. Keywords: Sacro-coccygeal teratoma, Growing teratoma syndromehttp://www.sciencedirect.com/science/article/pii/S2213576618303464 |
| spellingShingle | Tamador Al-Shamaileh Fatena Ajlouni Rasha Deebajah Iyad Sultan Mohammad M. Saleem Khalil Ghandour Malignant sacro-coccygeal teratoma with growing teratoma syndrome Journal of Pediatric Surgery Case Reports |
| title | Malignant sacro-coccygeal teratoma with growing teratoma syndrome |
| title_full | Malignant sacro-coccygeal teratoma with growing teratoma syndrome |
| title_fullStr | Malignant sacro-coccygeal teratoma with growing teratoma syndrome |
| title_full_unstemmed | Malignant sacro-coccygeal teratoma with growing teratoma syndrome |
| title_short | Malignant sacro-coccygeal teratoma with growing teratoma syndrome |
| title_sort | malignant sacro coccygeal teratoma with growing teratoma syndrome |
| url | http://www.sciencedirect.com/science/article/pii/S2213576618303464 |
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