Hospital Outcomes in Antepartum Mental Disorders: A Study on 897,397 Pregnant Inpatients

Objective: To evaluate the impact of antepartum mental disorders (AMD) in medical and psychiatric comorbidities, and inpatient outcomes during hospitalizations for pregnancy/birth-related complications. Methods: We used the national inpatient sample (NIS) data and included 19,170,562 female patients...

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Main Authors: Narmada N. Bhimanadham, Pranita Mainali, Chris A. Robert, Anum Masroor, Henry K. Onyeaka, Sadaf Hossain, Rikinkumar S. Patel
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Behavioral Sciences
Subjects:
Online Access:https://www.mdpi.com/2076-328X/9/10/105
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author Narmada N. Bhimanadham
Pranita Mainali
Chris A. Robert
Anum Masroor
Henry K. Onyeaka
Sadaf Hossain
Rikinkumar S. Patel
author_facet Narmada N. Bhimanadham
Pranita Mainali
Chris A. Robert
Anum Masroor
Henry K. Onyeaka
Sadaf Hossain
Rikinkumar S. Patel
author_sort Narmada N. Bhimanadham
collection DOAJ
description Objective: To evaluate the impact of antepartum mental disorders (AMD) in medical and psychiatric comorbidities, and inpatient outcomes during hospitalizations for pregnancy/birth-related complications. Methods: We used the national inpatient sample (NIS) data and included 19,170,562 female patients (age, 12&#8722;40 years) with a principal diagnosis of pregnancy/birth-related complications and grouped by co-diagnoses of AMD (N = 897,397). We used a binomial logistic regression model to evaluate the odds ratio (OR) for major severity of illness and adjusted for demographic confounders. Results: The hospitalizations with AMD increased by 22.1% (<i>p</i> &lt; 0.001) from 2010 to 2014. White females (66.1%) and those from low-income families (&lt;25th percentile, 31.8%) majorly had comorbid AMD. Depression (43.8%) and drug abuse (27%) were prevalent psychiatric disorders in AMD inpatients. Comorbid AMD inpatients had a higher likelihood for major severity of illness (OR 2.475, 95% CI 2.459&#8722;2.491, <i>p</i> &lt; 0.001). They also had a longer hospitalization stay with a mean difference of 0.486 days (95% CI 0.480&#8722;0.491) and higher total charges by $1889.420 per admission (95% CI 1852.670&#8722;1926.170) than non-AMD inpatients. Conclusions: AMD is associated with worsening of severity of illness in pregnancy/birth-related complications and require acute inpatient care. Mental health assessment and treatment of AMD, and education about efficacy and safety of psychiatric medications may help to improve outcomes in these patients.
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spelling doaj.art-f201d322de424444b1291de5ade7a2112022-12-22T01:08:56ZengMDPI AGBehavioral Sciences2076-328X2019-09-0191010510.3390/bs9100105bs9100105Hospital Outcomes in Antepartum Mental Disorders: A Study on 897,397 Pregnant InpatientsNarmada N. Bhimanadham0Pranita Mainali1Chris A. Robert2Anum Masroor3Henry K. Onyeaka4Sadaf Hossain5Rikinkumar S. Patel6Department of Public Administration, Drake University, Des Moines, IA 50311, USADepartment of Psychiatry, Washington DC VA Medical Center, Washington, DC 20422, USADepartment of Gynecology, Rao Hospital, Coimbatore 641002, IndiaDepartment of Psychiatry, Khyber Medical College, Khyber Pakhtunkhwa 25120, PakistanDepartment of Public Health, Harvard School of Public Health, Boston, MA 02115, USADepartment of Psychiatry, Brookdale Hospital and Medical Center, Brooklyn, NY 11212, USADepartment of Psychiatry, Griffin Memorial Hospital, Norman, OK 73071, USAObjective: To evaluate the impact of antepartum mental disorders (AMD) in medical and psychiatric comorbidities, and inpatient outcomes during hospitalizations for pregnancy/birth-related complications. Methods: We used the national inpatient sample (NIS) data and included 19,170,562 female patients (age, 12&#8722;40 years) with a principal diagnosis of pregnancy/birth-related complications and grouped by co-diagnoses of AMD (N = 897,397). We used a binomial logistic regression model to evaluate the odds ratio (OR) for major severity of illness and adjusted for demographic confounders. Results: The hospitalizations with AMD increased by 22.1% (<i>p</i> &lt; 0.001) from 2010 to 2014. White females (66.1%) and those from low-income families (&lt;25th percentile, 31.8%) majorly had comorbid AMD. Depression (43.8%) and drug abuse (27%) were prevalent psychiatric disorders in AMD inpatients. Comorbid AMD inpatients had a higher likelihood for major severity of illness (OR 2.475, 95% CI 2.459&#8722;2.491, <i>p</i> &lt; 0.001). They also had a longer hospitalization stay with a mean difference of 0.486 days (95% CI 0.480&#8722;0.491) and higher total charges by $1889.420 per admission (95% CI 1852.670&#8722;1926.170) than non-AMD inpatients. Conclusions: AMD is associated with worsening of severity of illness in pregnancy/birth-related complications and require acute inpatient care. Mental health assessment and treatment of AMD, and education about efficacy and safety of psychiatric medications may help to improve outcomes in these patients.https://www.mdpi.com/2076-328X/9/10/105pregnancycomplicationsantepartummental illnessdepressionoutcomespsychiatric disorder
spellingShingle Narmada N. Bhimanadham
Pranita Mainali
Chris A. Robert
Anum Masroor
Henry K. Onyeaka
Sadaf Hossain
Rikinkumar S. Patel
Hospital Outcomes in Antepartum Mental Disorders: A Study on 897,397 Pregnant Inpatients
Behavioral Sciences
pregnancy
complications
antepartum
mental illness
depression
outcomes
psychiatric disorder
title Hospital Outcomes in Antepartum Mental Disorders: A Study on 897,397 Pregnant Inpatients
title_full Hospital Outcomes in Antepartum Mental Disorders: A Study on 897,397 Pregnant Inpatients
title_fullStr Hospital Outcomes in Antepartum Mental Disorders: A Study on 897,397 Pregnant Inpatients
title_full_unstemmed Hospital Outcomes in Antepartum Mental Disorders: A Study on 897,397 Pregnant Inpatients
title_short Hospital Outcomes in Antepartum Mental Disorders: A Study on 897,397 Pregnant Inpatients
title_sort hospital outcomes in antepartum mental disorders a study on 897 397 pregnant inpatients
topic pregnancy
complications
antepartum
mental illness
depression
outcomes
psychiatric disorder
url https://www.mdpi.com/2076-328X/9/10/105
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