The mechanism underlying transient weakness in myotonia congenita

The mechanism underlying transient weakness in myotonia congenita

In addition to the hallmark muscle stiffness, patients with recessive myotonia congenita (Becker disease) experience debilitating bouts of transient weakness that remain poorly understood despite years of study. We performed intracellular recordings from muscle of both genetic and pharmacologic mous...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron:	Jessica H Myers, Kirsten Denman, Chris DuPont, Ahmed A Hawash, Kevin R Novak, Andrew Koesters, Manfred Grabner, Anamika Dayal, Andrew A Voss, Mark M Rich
Fformat:	Erthygl
Iaith:	English
Cyhoeddwyd:	eLife Sciences Publications Ltd 2021-04-01
Cyfres:	eLife
Pynciau:	muscle fiber myotonia sodium channel calcium channel persistent sodium current excitability
Mynediad Ar-lein:	https://elifesciences.org/articles/65691

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