The mechanism underlying transient weakness in myotonia congenita

The mechanism underlying transient weakness in myotonia congenita

In addition to the hallmark muscle stiffness, patients with recessive myotonia congenita (Becker disease) experience debilitating bouts of transient weakness that remain poorly understood despite years of study. We performed intracellular recordings from muscle of both genetic and pharmacologic mous...

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Chi tiết về thư mục
Những tác giả chính:	Jessica H Myers, Kirsten Denman, Chris DuPont, Ahmed A Hawash, Kevin R Novak, Andrew Koesters, Manfred Grabner, Anamika Dayal, Andrew A Voss, Mark M Rich
Định dạng:	Bài viết
Ngôn ngữ:	English
Được phát hành:	eLife Sciences Publications Ltd 2021-04-01
Loạt:	eLife
Những chủ đề:	muscle fiber myotonia sodium channel calcium channel persistent sodium current excitability
Truy cập trực tuyến:	https://elifesciences.org/articles/65691

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