The mechanism underlying transient weakness in myotonia congenita

The mechanism underlying transient weakness in myotonia congenita

In addition to the hallmark muscle stiffness, patients with recessive myotonia congenita (Becker disease) experience debilitating bouts of transient weakness that remain poorly understood despite years of study. We performed intracellular recordings from muscle of both genetic and pharmacologic mous...

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Dades bibliogràfiques
Autors principals: Jessica H Myers, Kirsten Denman, Chris DuPont, Ahmed A Hawash, Kevin R Novak, Andrew Koesters, Manfred Grabner, Anamika Dayal, Andrew A Voss, Mark M Rich
Format: Article
Idioma:English
Publicat: eLife Sciences Publications Ltd 2021-04-01
Col·lecció:eLife
Matèries:
muscle fiber
myotonia
sodium channel
calcium channel
persistent sodium current
excitability
Accés en línia:https://elifesciences.org/articles/65691

Internet

https://elifesciences.org/articles/65691

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