Angiotensin-(1–7) Receptor Mas Deficiency Does Not Exacerbate Cardiac Atrophy Following High-Level Spinal Cord Injury in Mice

Angiotensin-(1–7) Receptor Mas Deficiency Does Not Exacerbate Cardiac Atrophy Following High-Level Spinal Cord Injury in Mice

Experimental spinal cord injury (SCI) causes a morphological and functional deterioration of the heart, in which the renin–angiotensin system (RAS) might play a role. The recently discovered non-canonical axis of RAS with angiotensin-(1–7) and its receptor Mas, which is associated with cardioprotect...

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Bibliographic Details
Main Authors: Anne Järve, Fatimunnisa Qadri, Mihail Todiras, Shirley Schmolke, Natalia Alenina, Michael Bader
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Physiology
Subjects:
renin–angiotensin system
cardiac atrophy
atrogenes
sympathetic nervous system
fibrosis
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2020.00203/full

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