Acute Kidney Injury and Hypothyroidism in a Patient with CKD
Acute kidney injury (AKI) in the setting of hypothyroidism has been documented in the literature. However, hypothyroidism is not generally considered a cause during investigation of an acute kidney injury. Most of the cases described have been reported in setting of rhabdomyolysis, while fewer cases...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-10-01
|
| Series: | Kidney and Dialysis |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2673-8236/2/4/48 |
| _version_ | 1797456826469449728 |
|---|---|
| author | Preeti Chandra Abdolreza Haririan Cinthia Drachenberg |
| author_facet | Preeti Chandra Abdolreza Haririan Cinthia Drachenberg |
| author_sort | Preeti Chandra |
| collection | DOAJ |
| description | Acute kidney injury (AKI) in the setting of hypothyroidism has been documented in the literature. However, hypothyroidism is not generally considered a cause during investigation of an acute kidney injury. Most of the cases described have been reported in setting of rhabdomyolysis, while fewer cases describe AKI occurring in the absence of rhabdomyolysis. Only rarely have case reports been supplemented by renal biopsy findings to ensure other etiologies of acute kidney injury were ruled out, and none of these reports have documented changes in the kidney that could be associated with the hypothyroid state. We report a case of AKI in chronic kidney disease in the absence of rhabdomyolysis, occurring during severe hypothyroidism, that resolved completely after achievement of a euthyroid state. In addition, we provide renal biopsy findings likely associated with the hypothyroid state. We propose that evaluation of the thyroid function should be considered in any patient during evaluation of an acute kidney injury. |
| first_indexed | 2024-03-09T16:13:25Z |
| format | Article |
| id | doaj.art-f20d547d873e471281ccb7881a2e25f0 |
| institution | Directory Open Access Journal |
| issn | 2673-8236 |
| language | English |
| last_indexed | 2024-03-09T16:13:25Z |
| publishDate | 2022-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Kidney and Dialysis |
| spelling | doaj.art-f20d547d873e471281ccb7881a2e25f02023-11-24T16:05:03ZengMDPI AGKidney and Dialysis2673-82362022-10-012453754410.3390/kidneydial2040048Acute Kidney Injury and Hypothyroidism in a Patient with CKDPreeti Chandra0Abdolreza Haririan1Cinthia Drachenberg2Division of Nephrology, University of Maryland School of Medicine, N3W143, 22 S Greene St., Baltimore, MD 21201, USADivision of Nephrology, University of Maryland School of Medicine, N3W143, 22 S Greene St., Baltimore, MD 21201, USADivision of Pathology, University of Maryland School of Medicine, 22 S Greene St., Baltimore, MD 21201, USAAcute kidney injury (AKI) in the setting of hypothyroidism has been documented in the literature. However, hypothyroidism is not generally considered a cause during investigation of an acute kidney injury. Most of the cases described have been reported in setting of rhabdomyolysis, while fewer cases describe AKI occurring in the absence of rhabdomyolysis. Only rarely have case reports been supplemented by renal biopsy findings to ensure other etiologies of acute kidney injury were ruled out, and none of these reports have documented changes in the kidney that could be associated with the hypothyroid state. We report a case of AKI in chronic kidney disease in the absence of rhabdomyolysis, occurring during severe hypothyroidism, that resolved completely after achievement of a euthyroid state. In addition, we provide renal biopsy findings likely associated with the hypothyroid state. We propose that evaluation of the thyroid function should be considered in any patient during evaluation of an acute kidney injury.https://www.mdpi.com/2673-8236/2/4/48acute kidney injuryhypothyroidismthyroid and renal dysfunction |
| spellingShingle | Preeti Chandra Abdolreza Haririan Cinthia Drachenberg Acute Kidney Injury and Hypothyroidism in a Patient with CKD Kidney and Dialysis acute kidney injury hypothyroidism thyroid and renal dysfunction |
| title | Acute Kidney Injury and Hypothyroidism in a Patient with CKD |
| title_full | Acute Kidney Injury and Hypothyroidism in a Patient with CKD |
| title_fullStr | Acute Kidney Injury and Hypothyroidism in a Patient with CKD |
| title_full_unstemmed | Acute Kidney Injury and Hypothyroidism in a Patient with CKD |
| title_short | Acute Kidney Injury and Hypothyroidism in a Patient with CKD |
| title_sort | acute kidney injury and hypothyroidism in a patient with ckd |
| topic | acute kidney injury hypothyroidism thyroid and renal dysfunction |
| url | https://www.mdpi.com/2673-8236/2/4/48 |
| work_keys_str_mv | AT preetichandra acutekidneyinjuryandhypothyroidisminapatientwithckd AT abdolrezaharirian acutekidneyinjuryandhypothyroidisminapatientwithckd AT cinthiadrachenberg acutekidneyinjuryandhypothyroidisminapatientwithckd |