Copper and Zinc Content in Infant Milk Formulae Available on the Polish Market and Contribution to Dietary Intake

The inappropriate concentration of copper (Cu) and zinc (Zn) in formulae for infants can lead to abnormal micronutrient intake and adverse health outcomes. This study aimed to determine the concentration of Cu and Zn in different formulae and evaluate the Cu/Zn ratio. Besides, the daily intake (DI)...

Full description

Bibliographic Details
Main Authors: Małgorzata Dobrzyńska, Sławomira Drzymała-Czyż, Karol Jakubowski, Szymon Kurek, Jarosław Walkowiak, Juliusz Przysławski
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Nutrients
Subjects:
Online Access:https://www.mdpi.com/2072-6643/13/8/2542
_version_ 1797522602233692160
author Małgorzata Dobrzyńska
Sławomira Drzymała-Czyż
Karol Jakubowski
Szymon Kurek
Jarosław Walkowiak
Juliusz Przysławski
author_facet Małgorzata Dobrzyńska
Sławomira Drzymała-Czyż
Karol Jakubowski
Szymon Kurek
Jarosław Walkowiak
Juliusz Przysławski
author_sort Małgorzata Dobrzyńska
collection DOAJ
description The inappropriate concentration of copper (Cu) and zinc (Zn) in formulae for infants can lead to abnormal micronutrient intake and adverse health outcomes. This study aimed to determine the concentration of Cu and Zn in different formulae and evaluate the Cu/Zn ratio. Besides, the daily intake (DI) of both micronutrients was estimated. Cu and Zn concentration in 103 formulae for infants, available in the Polish market, were assessed using atomic absorption spectrometry. The estimated DI was calculated from the average energy requirements for the 0–6 months aged infants. The microelement content of formulae was mostly in good agreement with that declared by the manufacturer (5–10% variations compared to the labeled values). The Cu/Zn ratio ranged from 1:8 to 1:25. The estimated DI of Cu was in the range of 0.14–1.11 mg/day. Six (6.7%) of the formulae did not meet the recommended range of Cu intake, especially during the first month of life and in the case of formulae for special medical purposes. The estimated DI of Zn varied from 2.27–11.25 mg/day. In most cases, the concentration of Cu and Zn in infant formulae was within the recommended range. It would be advisable to consider monitoring the DI of Cu and reconsider the Cu content in formulae for infants in proportion to its expected consumption.
first_indexed 2024-03-10T08:31:44Z
format Article
id doaj.art-f20ec910bab641c9bae108ae5914c919
institution Directory Open Access Journal
issn 2072-6643
language English
last_indexed 2024-03-10T08:31:44Z
publishDate 2021-07-01
publisher MDPI AG
record_format Article
series Nutrients
spelling doaj.art-f20ec910bab641c9bae108ae5914c9192023-11-22T09:02:17ZengMDPI AGNutrients2072-66432021-07-01138254210.3390/nu13082542Copper and Zinc Content in Infant Milk Formulae Available on the Polish Market and Contribution to Dietary IntakeMałgorzata Dobrzyńska0Sławomira Drzymała-Czyż1Karol Jakubowski2Szymon Kurek3Jarosław Walkowiak4Juliusz Przysławski5Department of Bromatology, Poznan University of Medical Sciences, 42 Marcelińska Street, 60-354 Poznań, PolandDepartment of Bromatology, Poznan University of Medical Sciences, 42 Marcelińska Street, 60-354 Poznań, PolandDepartment of Bromatology, Poznan University of Medical Sciences, 42 Marcelińska Street, 60-354 Poznań, PolandDepartment of Pediatric Gastroenterology and Metabolic Diseases, Poznan University of Medical Sciences, 27/33 Szpitalna Street, 60-572 Poznań, PolandDepartment of Pediatric Gastroenterology and Metabolic Diseases, Poznan University of Medical Sciences, 27/33 Szpitalna Street, 60-572 Poznań, PolandDepartment of Bromatology, Poznan University of Medical Sciences, 42 Marcelińska Street, 60-354 Poznań, PolandThe inappropriate concentration of copper (Cu) and zinc (Zn) in formulae for infants can lead to abnormal micronutrient intake and adverse health outcomes. This study aimed to determine the concentration of Cu and Zn in different formulae and evaluate the Cu/Zn ratio. Besides, the daily intake (DI) of both micronutrients was estimated. Cu and Zn concentration in 103 formulae for infants, available in the Polish market, were assessed using atomic absorption spectrometry. The estimated DI was calculated from the average energy requirements for the 0–6 months aged infants. The microelement content of formulae was mostly in good agreement with that declared by the manufacturer (5–10% variations compared to the labeled values). The Cu/Zn ratio ranged from 1:8 to 1:25. The estimated DI of Cu was in the range of 0.14–1.11 mg/day. Six (6.7%) of the formulae did not meet the recommended range of Cu intake, especially during the first month of life and in the case of formulae for special medical purposes. The estimated DI of Zn varied from 2.27–11.25 mg/day. In most cases, the concentration of Cu and Zn in infant formulae was within the recommended range. It would be advisable to consider monitoring the DI of Cu and reconsider the Cu content in formulae for infants in proportion to its expected consumption.https://www.mdpi.com/2072-6643/13/8/2542micronutrientsinfant formulafollow-on formulaformula for special medical purposesdaily intake
spellingShingle Małgorzata Dobrzyńska
Sławomira Drzymała-Czyż
Karol Jakubowski
Szymon Kurek
Jarosław Walkowiak
Juliusz Przysławski
Copper and Zinc Content in Infant Milk Formulae Available on the Polish Market and Contribution to Dietary Intake
Nutrients
micronutrients
infant formula
follow-on formula
formula for special medical purposes
daily intake
title Copper and Zinc Content in Infant Milk Formulae Available on the Polish Market and Contribution to Dietary Intake
title_full Copper and Zinc Content in Infant Milk Formulae Available on the Polish Market and Contribution to Dietary Intake
title_fullStr Copper and Zinc Content in Infant Milk Formulae Available on the Polish Market and Contribution to Dietary Intake
title_full_unstemmed Copper and Zinc Content in Infant Milk Formulae Available on the Polish Market and Contribution to Dietary Intake
title_short Copper and Zinc Content in Infant Milk Formulae Available on the Polish Market and Contribution to Dietary Intake
title_sort copper and zinc content in infant milk formulae available on the polish market and contribution to dietary intake
topic micronutrients
infant formula
follow-on formula
formula for special medical purposes
daily intake
url https://www.mdpi.com/2072-6643/13/8/2542
work_keys_str_mv AT małgorzatadobrzynska copperandzinccontentininfantmilkformulaeavailableonthepolishmarketandcontributiontodietaryintake
AT sławomiradrzymałaczyz copperandzinccontentininfantmilkformulaeavailableonthepolishmarketandcontributiontodietaryintake
AT karoljakubowski copperandzinccontentininfantmilkformulaeavailableonthepolishmarketandcontributiontodietaryintake
AT szymonkurek copperandzinccontentininfantmilkformulaeavailableonthepolishmarketandcontributiontodietaryintake
AT jarosławwalkowiak copperandzinccontentininfantmilkformulaeavailableonthepolishmarketandcontributiontodietaryintake
AT juliuszprzysławski copperandzinccontentininfantmilkformulaeavailableonthepolishmarketandcontributiontodietaryintake