The role of the complement system in disc degeneration and Modic changes

The role of the complement system in disc degeneration and Modic changes

Abstract Disc degeneration and vertebral endplate bone marrow lesions called Modic changes are prevalent spinal pathologies found in chronic low back pain patients. Their pathomechanisms are complex and not fully understood. Recent studies have revealed that complement system proteins and interactor...

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Bibliographic Details
Main Authors: Irina Heggli, Graciosa Q. Teixeira, James C. Iatridis, Cornelia Neidlinger‐Wilke, Stefan Dudli
Format: Article
Language:English
Published: Wiley 2024-03-01
Series:JOR Spine
Subjects:
complement system
disc degeneration
low back pain
Modic changes
Online Access:https://doi.org/10.1002/jsp2.1312

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