Outcomes of Intrathecal Baclofen Therapy Compared With Deep Brain Stimulation in a Patient With Dystonic Cerebral Palsy: A Case Report

Deep brain stimulation (DBS) in internal globus pallidus is considered to be a good option for controlling generalized dystonia in patients with this condition. In this relation, it is known that DBS has already been shown to have significant effects on primary dystonia, but is seen as controversial...

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Main Authors: Minji Chae, Seungbeen Hong, Na Young Jung, Won Seok Chang, Sung-Rae Cho
Format: Article
Language:English
Published: Korean Academy of Rehabilitation Medicine 2019-06-01
Series:Annals of Rehabilitation Medicine
Subjects:
Online Access:http://www.e-arm.org/upload/pdf/arm-2019-43-3-335.pdf
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author Minji Chae
Seungbeen Hong
Na Young Jung
Won Seok Chang
Sung-Rae Cho
author_facet Minji Chae
Seungbeen Hong
Na Young Jung
Won Seok Chang
Sung-Rae Cho
author_sort Minji Chae
collection DOAJ
description Deep brain stimulation (DBS) in internal globus pallidus is considered to be a good option for controlling generalized dystonia in patients with this condition. In this relation, it is known that DBS has already been shown to have significant effects on primary dystonia, but is seen as controversial in secondary dystonia including cerebral palsy (CP). On the other hand, intrathecal baclofen (ITB) has been known to reduce spasticity and dystonia in patients who did not respond to oral medications or botulinum toxin treatment. Here, we report a patient with dystonic CP, who received the ITB pump implantation long after the DBS and who noted remarkable improvement in the 36-Item Short Form Health Survey, Dystonia Rating Scale, Modified Barthel Index, and visual analog scale scores for pain after an ITB pump implantation was used as compared with DBS. To our knowledge, the present case report is the first to demonstrate the effects of an ITB pump on reducing pain and dystonia and improving quality of life and satisfaction, compared with DBS in a patient with CP.
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spelling doaj.art-f2197df1b145453ea27f395d28351c912023-09-03T05:56:37ZengKorean Academy of Rehabilitation MedicineAnnals of Rehabilitation Medicine2234-06452234-06532019-06-0143333534010.5535/arm.2019.43.3.3354105Outcomes of Intrathecal Baclofen Therapy Compared With Deep Brain Stimulation in a Patient With Dystonic Cerebral Palsy: A Case ReportMinji Chae0Seungbeen Hong1Na Young Jung2Won Seok Chang3Sung-Rae Cho4 Department of Rehabilitation Medicine and Research Institute of Rehabilitation Medicine, Yonsei University College of Medicine, Seoul, Korea Department of Rehabilitation Medicine and Research Institute of Rehabilitation Medicine, Yonsei University College of Medicine, Seoul, Korea Department of Neurosurgery and Brain Research Institute, Yonsei University College of Medicine, Seoul, Korea Department of Neurosurgery and Brain Research Institute, Yonsei University College of Medicine, Seoul, Korea Department of Rehabilitation Medicine and Research Institute of Rehabilitation Medicine, Yonsei University College of Medicine, Seoul, KoreaDeep brain stimulation (DBS) in internal globus pallidus is considered to be a good option for controlling generalized dystonia in patients with this condition. In this relation, it is known that DBS has already been shown to have significant effects on primary dystonia, but is seen as controversial in secondary dystonia including cerebral palsy (CP). On the other hand, intrathecal baclofen (ITB) has been known to reduce spasticity and dystonia in patients who did not respond to oral medications or botulinum toxin treatment. Here, we report a patient with dystonic CP, who received the ITB pump implantation long after the DBS and who noted remarkable improvement in the 36-Item Short Form Health Survey, Dystonia Rating Scale, Modified Barthel Index, and visual analog scale scores for pain after an ITB pump implantation was used as compared with DBS. To our knowledge, the present case report is the first to demonstrate the effects of an ITB pump on reducing pain and dystonia and improving quality of life and satisfaction, compared with DBS in a patient with CP.http://www.e-arm.org/upload/pdf/arm-2019-43-3-335.pdfDystoniaIntrathecal baclofen pumpDeep brain stimulationCerebral palsy
spellingShingle Minji Chae
Seungbeen Hong
Na Young Jung
Won Seok Chang
Sung-Rae Cho
Outcomes of Intrathecal Baclofen Therapy Compared With Deep Brain Stimulation in a Patient With Dystonic Cerebral Palsy: A Case Report
Annals of Rehabilitation Medicine
Dystonia
Intrathecal baclofen pump
Deep brain stimulation
Cerebral palsy
title Outcomes of Intrathecal Baclofen Therapy Compared With Deep Brain Stimulation in a Patient With Dystonic Cerebral Palsy: A Case Report
title_full Outcomes of Intrathecal Baclofen Therapy Compared With Deep Brain Stimulation in a Patient With Dystonic Cerebral Palsy: A Case Report
title_fullStr Outcomes of Intrathecal Baclofen Therapy Compared With Deep Brain Stimulation in a Patient With Dystonic Cerebral Palsy: A Case Report
title_full_unstemmed Outcomes of Intrathecal Baclofen Therapy Compared With Deep Brain Stimulation in a Patient With Dystonic Cerebral Palsy: A Case Report
title_short Outcomes of Intrathecal Baclofen Therapy Compared With Deep Brain Stimulation in a Patient With Dystonic Cerebral Palsy: A Case Report
title_sort outcomes of intrathecal baclofen therapy compared with deep brain stimulation in a patient with dystonic cerebral palsy a case report
topic Dystonia
Intrathecal baclofen pump
Deep brain stimulation
Cerebral palsy
url http://www.e-arm.org/upload/pdf/arm-2019-43-3-335.pdf
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