Outcomes of Intrathecal Baclofen Therapy Compared With Deep Brain Stimulation in a Patient With Dystonic Cerebral Palsy: A Case Report
Deep brain stimulation (DBS) in internal globus pallidus is considered to be a good option for controlling generalized dystonia in patients with this condition. In this relation, it is known that DBS has already been shown to have significant effects on primary dystonia, but is seen as controversial...
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| Format: | Article |
| Language: | English |
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Korean Academy of Rehabilitation Medicine
2019-06-01
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| Series: | Annals of Rehabilitation Medicine |
| Subjects: | |
| Online Access: | http://www.e-arm.org/upload/pdf/arm-2019-43-3-335.pdf |
| _version_ | 1827834033488265216 |
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| author | Minji Chae Seungbeen Hong Na Young Jung Won Seok Chang Sung-Rae Cho |
| author_facet | Minji Chae Seungbeen Hong Na Young Jung Won Seok Chang Sung-Rae Cho |
| author_sort | Minji Chae |
| collection | DOAJ |
| description | Deep brain stimulation (DBS) in internal globus pallidus is considered to be a good option for controlling generalized dystonia in patients with this condition. In this relation, it is known that DBS has already been shown to have significant effects on primary dystonia, but is seen as controversial in secondary dystonia including cerebral palsy (CP). On the other hand, intrathecal baclofen (ITB) has been known to reduce spasticity and dystonia in patients who did not respond to oral medications or botulinum toxin treatment. Here, we report a patient with dystonic CP, who received the ITB pump implantation long after the DBS and who noted remarkable improvement in the 36-Item Short Form Health Survey, Dystonia Rating Scale, Modified Barthel Index, and visual analog scale scores for pain after an ITB pump implantation was used as compared with DBS. To our knowledge, the present case report is the first to demonstrate the effects of an ITB pump on reducing pain and dystonia and improving quality of life and satisfaction, compared with DBS in a patient with CP. |
| first_indexed | 2024-03-12T05:43:01Z |
| format | Article |
| id | doaj.art-f2197df1b145453ea27f395d28351c91 |
| institution | Directory Open Access Journal |
| issn | 2234-0645 2234-0653 |
| language | English |
| last_indexed | 2024-03-12T05:43:01Z |
| publishDate | 2019-06-01 |
| publisher | Korean Academy of Rehabilitation Medicine |
| record_format | Article |
| series | Annals of Rehabilitation Medicine |
| spelling | doaj.art-f2197df1b145453ea27f395d28351c912023-09-03T05:56:37ZengKorean Academy of Rehabilitation MedicineAnnals of Rehabilitation Medicine2234-06452234-06532019-06-0143333534010.5535/arm.2019.43.3.3354105Outcomes of Intrathecal Baclofen Therapy Compared With Deep Brain Stimulation in a Patient With Dystonic Cerebral Palsy: A Case ReportMinji Chae0Seungbeen Hong1Na Young Jung2Won Seok Chang3Sung-Rae Cho4 Department of Rehabilitation Medicine and Research Institute of Rehabilitation Medicine, Yonsei University College of Medicine, Seoul, Korea Department of Rehabilitation Medicine and Research Institute of Rehabilitation Medicine, Yonsei University College of Medicine, Seoul, Korea Department of Neurosurgery and Brain Research Institute, Yonsei University College of Medicine, Seoul, Korea Department of Neurosurgery and Brain Research Institute, Yonsei University College of Medicine, Seoul, Korea Department of Rehabilitation Medicine and Research Institute of Rehabilitation Medicine, Yonsei University College of Medicine, Seoul, KoreaDeep brain stimulation (DBS) in internal globus pallidus is considered to be a good option for controlling generalized dystonia in patients with this condition. In this relation, it is known that DBS has already been shown to have significant effects on primary dystonia, but is seen as controversial in secondary dystonia including cerebral palsy (CP). On the other hand, intrathecal baclofen (ITB) has been known to reduce spasticity and dystonia in patients who did not respond to oral medications or botulinum toxin treatment. Here, we report a patient with dystonic CP, who received the ITB pump implantation long after the DBS and who noted remarkable improvement in the 36-Item Short Form Health Survey, Dystonia Rating Scale, Modified Barthel Index, and visual analog scale scores for pain after an ITB pump implantation was used as compared with DBS. To our knowledge, the present case report is the first to demonstrate the effects of an ITB pump on reducing pain and dystonia and improving quality of life and satisfaction, compared with DBS in a patient with CP.http://www.e-arm.org/upload/pdf/arm-2019-43-3-335.pdfDystoniaIntrathecal baclofen pumpDeep brain stimulationCerebral palsy |
| spellingShingle | Minji Chae Seungbeen Hong Na Young Jung Won Seok Chang Sung-Rae Cho Outcomes of Intrathecal Baclofen Therapy Compared With Deep Brain Stimulation in a Patient With Dystonic Cerebral Palsy: A Case Report Annals of Rehabilitation Medicine Dystonia Intrathecal baclofen pump Deep brain stimulation Cerebral palsy |
| title | Outcomes of Intrathecal Baclofen Therapy Compared With Deep Brain Stimulation in a Patient With Dystonic Cerebral Palsy: A Case Report |
| title_full | Outcomes of Intrathecal Baclofen Therapy Compared With Deep Brain Stimulation in a Patient With Dystonic Cerebral Palsy: A Case Report |
| title_fullStr | Outcomes of Intrathecal Baclofen Therapy Compared With Deep Brain Stimulation in a Patient With Dystonic Cerebral Palsy: A Case Report |
| title_full_unstemmed | Outcomes of Intrathecal Baclofen Therapy Compared With Deep Brain Stimulation in a Patient With Dystonic Cerebral Palsy: A Case Report |
| title_short | Outcomes of Intrathecal Baclofen Therapy Compared With Deep Brain Stimulation in a Patient With Dystonic Cerebral Palsy: A Case Report |
| title_sort | outcomes of intrathecal baclofen therapy compared with deep brain stimulation in a patient with dystonic cerebral palsy a case report |
| topic | Dystonia Intrathecal baclofen pump Deep brain stimulation Cerebral palsy |
| url | http://www.e-arm.org/upload/pdf/arm-2019-43-3-335.pdf |
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