Personality disorders as predictors for the conversion from major depressive disorder to bipolar disorder: A prospective cohort study
Studies suggest that personality disorders can predict mood disorders. The present study aims to assess whether personality traits in individuals with major depressive disorder (MDD) can predict the conversion to bipolar disorder (BD). This was a prospective cohort study conducted in two waves. In t...
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| Format: | Article |
| Language: | English |
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Elsevier
2022-09-01
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| Series: | Psychiatry Research Communications |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2772598722000496 |
| _version_ | 1798001177068044288 |
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| author | Gisele Bartz de Ávila Bruno Braga Montezano Luciano Dias de Mattos Souza Taiane de Azevedo Cardoso Ricardo Azevedo da Silva Thaíse Campos Mondin Fernanda Pedrotti Moreira Karen Jansen |
| author_facet | Gisele Bartz de Ávila Bruno Braga Montezano Luciano Dias de Mattos Souza Taiane de Azevedo Cardoso Ricardo Azevedo da Silva Thaíse Campos Mondin Fernanda Pedrotti Moreira Karen Jansen |
| author_sort | Gisele Bartz de Ávila |
| collection | DOAJ |
| description | Studies suggest that personality disorders can predict mood disorders. The present study aims to assess whether personality traits in individuals with major depressive disorder (MDD) can predict the conversion to bipolar disorder (BD). This was a prospective cohort study conducted in two waves. In the first wave, 585 subjects were diagnosed with MDD; in the second wave, all of them were reevaluated in a three-year follow-up. Personality traits were evaluated, in the first phase, using the Millon Clinical Multiaxial Inventory (MCMI). MDD and BD diagnosis was performed by trained psychologists using a clinical structured interview based on diagnostics criteria of DSM IV, the Mini International Neuropsychiatric Interview, Plus version (MINI-PLUS). During the second wave, 468 individuals were reevaluated. Diagnostic conversion rate from MDD to BD was 12.4%. Higher mean scores in Antissocial, Borderline personality traits and in the sum of all Cluster B disorders were found among individuals who had converted to BD. In addition, individuals who converted to BD had lowest scores in obsessive-compulsive personality traits. Our findings suggest that Cluster B personality disorders can be considered as predictors of diagnostics conversion from MDD to BD. Also, it seems that obsessive-compulsive traits were lower among those individuals who have converted to BD. |
| first_indexed | 2024-04-11T11:31:59Z |
| format | Article |
| id | doaj.art-f226ec2eb2ec469192e297c7d83d2da0 |
| institution | Directory Open Access Journal |
| issn | 2772-5987 |
| language | English |
| last_indexed | 2024-04-11T11:31:59Z |
| publishDate | 2022-09-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Psychiatry Research Communications |
| spelling | doaj.art-f226ec2eb2ec469192e297c7d83d2da02022-12-22T04:26:07ZengElsevierPsychiatry Research Communications2772-59872022-09-0123100068Personality disorders as predictors for the conversion from major depressive disorder to bipolar disorder: A prospective cohort studyGisele Bartz de Ávila0Bruno Braga Montezano1Luciano Dias de Mattos Souza2Taiane de Azevedo Cardoso3Ricardo Azevedo da Silva4Thaíse Campos Mondin5Fernanda Pedrotti Moreira6Karen Jansen7Department of Health and Behavior, Catholic University of Pelotas, Pelotas, RS, BrazilDepartment of Health and Behavior, Catholic University of Pelotas, Pelotas, RS, BrazilDepartment of Health and Behavior, Catholic University of Pelotas, Pelotas, RS, BrazilMood Disorders Program, Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, ON, CanadaDepartment of Health and Behavior, Catholic University of Pelotas, Pelotas, RS, BrazilDepartment of Student Affairs, Federal University of Pelotas, Pelotas, RS, BrazilDepartment of Health and Behavior, Catholic University of Pelotas, Pelotas, RS, BrazilDepartment of Health and Behavior, Catholic University of Pelotas, Pelotas, RS, Brazil; Corresponding author. 373, Gonçalves Chaves, Centro, Pelotas, RS, BrazilStudies suggest that personality disorders can predict mood disorders. The present study aims to assess whether personality traits in individuals with major depressive disorder (MDD) can predict the conversion to bipolar disorder (BD). This was a prospective cohort study conducted in two waves. In the first wave, 585 subjects were diagnosed with MDD; in the second wave, all of them were reevaluated in a three-year follow-up. Personality traits were evaluated, in the first phase, using the Millon Clinical Multiaxial Inventory (MCMI). MDD and BD diagnosis was performed by trained psychologists using a clinical structured interview based on diagnostics criteria of DSM IV, the Mini International Neuropsychiatric Interview, Plus version (MINI-PLUS). During the second wave, 468 individuals were reevaluated. Diagnostic conversion rate from MDD to BD was 12.4%. Higher mean scores in Antissocial, Borderline personality traits and in the sum of all Cluster B disorders were found among individuals who had converted to BD. In addition, individuals who converted to BD had lowest scores in obsessive-compulsive personality traits. Our findings suggest that Cluster B personality disorders can be considered as predictors of diagnostics conversion from MDD to BD. Also, it seems that obsessive-compulsive traits were lower among those individuals who have converted to BD.http://www.sciencedirect.com/science/article/pii/S2772598722000496Personality disordersMajor depressive disorderBipolar disorderDiagnostic conversionCohort study |
| spellingShingle | Gisele Bartz de Ávila Bruno Braga Montezano Luciano Dias de Mattos Souza Taiane de Azevedo Cardoso Ricardo Azevedo da Silva Thaíse Campos Mondin Fernanda Pedrotti Moreira Karen Jansen Personality disorders as predictors for the conversion from major depressive disorder to bipolar disorder: A prospective cohort study Psychiatry Research Communications Personality disorders Major depressive disorder Bipolar disorder Diagnostic conversion Cohort study |
| title | Personality disorders as predictors for the conversion from major depressive disorder to bipolar disorder: A prospective cohort study |
| title_full | Personality disorders as predictors for the conversion from major depressive disorder to bipolar disorder: A prospective cohort study |
| title_fullStr | Personality disorders as predictors for the conversion from major depressive disorder to bipolar disorder: A prospective cohort study |
| title_full_unstemmed | Personality disorders as predictors for the conversion from major depressive disorder to bipolar disorder: A prospective cohort study |
| title_short | Personality disorders as predictors for the conversion from major depressive disorder to bipolar disorder: A prospective cohort study |
| title_sort | personality disorders as predictors for the conversion from major depressive disorder to bipolar disorder a prospective cohort study |
| topic | Personality disorders Major depressive disorder Bipolar disorder Diagnostic conversion Cohort study |
| url | http://www.sciencedirect.com/science/article/pii/S2772598722000496 |
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