Disseminated primary herpes simplex infection imitating preterm prelabor rupture of membranes – a case report
Background: We describe a case of primary herpes simplex virus (HSV) infection imitating preterm prelabor rupture of membranes (PPROM) and review the intricacies of establishing the diagnosis. Case presentation: At 18 weeks of gestation, a patient was referred for suspected PPROM following leakage o...
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| Format: | Article |
| Language: | English |
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Elsevier
2023-09-01
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| Series: | Case Reports in Women's Health |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2214911223000528 |
| _version_ | 1827781506382168064 |
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| author | Dylan Campbell Henry Lesser Robert M. Ehsanipoor |
| author_facet | Dylan Campbell Henry Lesser Robert M. Ehsanipoor |
| author_sort | Dylan Campbell |
| collection | DOAJ |
| description | Background: We describe a case of primary herpes simplex virus (HSV) infection imitating preterm prelabor rupture of membranes (PPROM) and review the intricacies of establishing the diagnosis. Case presentation: At 18 weeks of gestation, a patient was referred for suspected PPROM following leakage of fluid and a positive nitrazine test. The patient had a swollen inguinal lymph node, intermittent fevers, transaminitis, labial lesions, and cervical ulceration with vaginal discharge. Amniotic fluid volume was normal. An HSV PCR test was positive. Intravenous acyclovir followed by oral valacyclovir resulted in resolution of symptoms. Conclusion: Discharge from HSV cervicitis can present as nitrazine-positive pooling, imitating PPROM. A high index of suspicion is warranted, especially when the amniotic fluid volume is normal and arborization is not seen on microscopic exam. |
| first_indexed | 2024-03-11T15:19:39Z |
| format | Article |
| id | doaj.art-f22cf60e0b07420ca49c912cad79b1ea |
| institution | Directory Open Access Journal |
| issn | 2214-9112 |
| language | English |
| last_indexed | 2024-03-11T15:19:39Z |
| publishDate | 2023-09-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Case Reports in Women's Health |
| spelling | doaj.art-f22cf60e0b07420ca49c912cad79b1ea2023-10-29T04:19:48ZengElsevierCase Reports in Women's Health2214-91122023-09-0139e00528Disseminated primary herpes simplex infection imitating preterm prelabor rupture of membranes – a case reportDylan Campbell0Henry Lesser1Robert M. Ehsanipoor2Corresponding author at: 2401 W Belvedere Ave, Baltimore, MD 21215, United States.; Sinai Hospital of Baltimore, Department of Obstetrics and Gynecology, Baltimore, MD, United StatesSinai Hospital of Baltimore, Department of Obstetrics and Gynecology, Baltimore, MD, United StatesSinai Hospital of Baltimore, Department of Obstetrics and Gynecology, Baltimore, MD, United StatesBackground: We describe a case of primary herpes simplex virus (HSV) infection imitating preterm prelabor rupture of membranes (PPROM) and review the intricacies of establishing the diagnosis. Case presentation: At 18 weeks of gestation, a patient was referred for suspected PPROM following leakage of fluid and a positive nitrazine test. The patient had a swollen inguinal lymph node, intermittent fevers, transaminitis, labial lesions, and cervical ulceration with vaginal discharge. Amniotic fluid volume was normal. An HSV PCR test was positive. Intravenous acyclovir followed by oral valacyclovir resulted in resolution of symptoms. Conclusion: Discharge from HSV cervicitis can present as nitrazine-positive pooling, imitating PPROM. A high index of suspicion is warranted, especially when the amniotic fluid volume is normal and arborization is not seen on microscopic exam.http://www.sciencedirect.com/science/article/pii/S2214911223000528Case reportPPROMHerpesAcyclovir |
| spellingShingle | Dylan Campbell Henry Lesser Robert M. Ehsanipoor Disseminated primary herpes simplex infection imitating preterm prelabor rupture of membranes – a case report Case Reports in Women's Health Case report PPROM Herpes Acyclovir |
| title | Disseminated primary herpes simplex infection imitating preterm prelabor rupture of membranes – a case report |
| title_full | Disseminated primary herpes simplex infection imitating preterm prelabor rupture of membranes – a case report |
| title_fullStr | Disseminated primary herpes simplex infection imitating preterm prelabor rupture of membranes – a case report |
| title_full_unstemmed | Disseminated primary herpes simplex infection imitating preterm prelabor rupture of membranes – a case report |
| title_short | Disseminated primary herpes simplex infection imitating preterm prelabor rupture of membranes – a case report |
| title_sort | disseminated primary herpes simplex infection imitating preterm prelabor rupture of membranes a case report |
| topic | Case report PPROM Herpes Acyclovir |
| url | http://www.sciencedirect.com/science/article/pii/S2214911223000528 |
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