The Ccr4-Not complex regulates TORC1 signaling and mitochondrial metabolism by promoting vacuole V-ATPase activity.
The Ccr4-Not complex functions as an effector of multiple signaling pathways that control gene transcription and mRNA turnover. Consequently, Ccr4-Not contributes to a diverse array of processes, which includes a significant role in cell metabolism. Yet a mechanistic understanding of how it contribu...
Main Authors: | Hongfeng Chen, P Winston Miller, Daniel L Johnson, R Nicholas Laribee |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2020-10-01
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Series: | PLoS Genetics |
Online Access: | https://doi.org/10.1371/journal.pgen.1009046 |
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