A Digital Signal Amplification Device for Microelectrode Arrays based on Stochastic Resonance

In this work, an experimental study was carried out about the construction of an amplification equipment based on the phenomenon of stochastic resonance (SR), which was initially thought to detect spikes and bursts from human and animal neuronal tissue, both in vitro (from microelectrode array, ME...

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Main Authors: FAMBRINI, F., DESTRO-FILHO, J. B., Del Val CURA, L. M., SAQUI, D., SAITO, J. H.
Format: Article
Language:English
Published: Stefan cel Mare University of Suceava 2020-08-01
Series:Advances in Electrical and Computer Engineering
Subjects:
Online Access:http://dx.doi.org/10.4316/AECE.2020.03004
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author FAMBRINI, F.
DESTRO-FILHO, J. B.
Del Val CURA, L. M.
SAQUI, D.
SAITO, J. H.
author_facet FAMBRINI, F.
DESTRO-FILHO, J. B.
Del Val CURA, L. M.
SAQUI, D.
SAITO, J. H.
author_sort FAMBRINI, F.
collection DOAJ
description In this work, an experimental study was carried out about the construction of an amplification equipment based on the phenomenon of stochastic resonance (SR), which was initially thought to detect spikes and bursts from human and animal neuronal tissue, both in vitro (from microelectrode array, MEA) and in vivo, from electrodes in the cerebral cortex of mammals. The implemented equipment was called CADSR (Computer-Aided Digital Stochastic Resonator) and brings as innovation the fact of being controlled and monitored by the computer, through a graphical interface that allows an automatic tuning, making it possible to obtain the optimum level of noise to maintain SR in real-time. Experimental results show that for electrical signals from multi-electrode arrays with amplitude below 25 microvolts, the amplification system using stochastic resonance is better than conventional amplifier systems, which use operational amplifiers in linear configurations.
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spelling doaj.art-f22e09840f30430e93baa814cb4571122022-12-21T18:57:09ZengStefan cel Mare University of SuceavaAdvances in Electrical and Computer Engineering1582-74451844-76002020-08-01203314010.4316/AECE.2020.03004A Digital Signal Amplification Device for Microelectrode Arrays based on Stochastic ResonanceFAMBRINI, F.DESTRO-FILHO, J. B.Del Val CURA, L. M.SAQUI, D.SAITO, J. H.In this work, an experimental study was carried out about the construction of an amplification equipment based on the phenomenon of stochastic resonance (SR), which was initially thought to detect spikes and bursts from human and animal neuronal tissue, both in vitro (from microelectrode array, MEA) and in vivo, from electrodes in the cerebral cortex of mammals. The implemented equipment was called CADSR (Computer-Aided Digital Stochastic Resonator) and brings as innovation the fact of being controlled and monitored by the computer, through a graphical interface that allows an automatic tuning, making it possible to obtain the optimum level of noise to maintain SR in real-time. Experimental results show that for electrical signals from multi-electrode arrays with amplitude below 25 microvolts, the amplification system using stochastic resonance is better than conventional amplifier systems, which use operational amplifiers in linear configurations.http://dx.doi.org/10.4316/AECE.2020.03004multielectrodesignalstochasticresonanceamplifier
spellingShingle FAMBRINI, F.
DESTRO-FILHO, J. B.
Del Val CURA, L. M.
SAQUI, D.
SAITO, J. H.
A Digital Signal Amplification Device for Microelectrode Arrays based on Stochastic Resonance
Advances in Electrical and Computer Engineering
multielectrode
signal
stochastic
resonance
amplifier
title A Digital Signal Amplification Device for Microelectrode Arrays based on Stochastic Resonance
title_full A Digital Signal Amplification Device for Microelectrode Arrays based on Stochastic Resonance
title_fullStr A Digital Signal Amplification Device for Microelectrode Arrays based on Stochastic Resonance
title_full_unstemmed A Digital Signal Amplification Device for Microelectrode Arrays based on Stochastic Resonance
title_short A Digital Signal Amplification Device for Microelectrode Arrays based on Stochastic Resonance
title_sort digital signal amplification device for microelectrode arrays based on stochastic resonance
topic multielectrode
signal
stochastic
resonance
amplifier
url http://dx.doi.org/10.4316/AECE.2020.03004
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