Telotristat ethyl reverses myxomatous changes in mice mitral valves

RationaleMyxomatous mitral valve degeneration is a common pathological manifestation of mitral valve regurgitation, with or without valvular prolapse. In addition to similarities between naturally occurring and serotonergic valve degeneration, an increasing body of evidence has recently suggested th...

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Bibliographic Details
Main Authors: Xinmei Wang, Danielle Kuban-Johnston, Pablo Lapuerta, Carla M. R. Lacerda
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2022.945672/full