Diffuse Presence of Myeloblasts in Chronic Subdural Hematoma of a Young Adult Patient without Systemic Hematologic Disorder
Abstract Objective Myeloblasts are rarely found in the composition of a chronic subdural hematoma (CSH), and reported cases with myeloblasts in CSH have all been associated with systemic hematologic disorders. We present a young man with CSH manifesting the diffuse presence of myeloblas...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Georg Thieme Verlag KG
2014-06-01
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| Series: | Journal of Neurological Surgery Reports |
| Subjects: | |
| Online Access: | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0034-1376199 |
| _version_ | 1811327345942855680 |
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| author | Shota Yokoyama Toru Fukuhara Yoichiro Namba Shoji Asakura |
| author_facet | Shota Yokoyama Toru Fukuhara Yoichiro Namba Shoji Asakura |
| author_sort | Shota Yokoyama |
| collection | DOAJ |
| description | Abstract
Objective Myeloblasts are rarely found in the composition of a chronic subdural hematoma (CSH), and reported cases with myeloblasts in CSH have all been associated with systemic hematologic disorders. We present a young man with CSH manifesting the diffuse presence of myeloblasts, although no systemic hematologic disorders were identified.
Participant A 27-year-old man, complaining of a headache lasting for a few months, was diagnosed with right CSH, and the aspirated hematoma was sent for cytological evaluation because no apparent etiologic episode was found. The diffuse presence of precursor cells, such as myeloblasts and erythroblasts, mimicking the aspirated bone marrow, was confirmed. This finding was suggestive of a systemic hematologic disorder, although the systemic evaluations were negative.
Results The patient's hematoma reaccumulated twice, and finally hematoma and enhanced dura were removed by craniotomy under general anesthesia. Further histologic evaluation did not show any precursor cells, and he has remained asymptomatic for > 2 years without any evidence of the hematologic disorder.
Conclusion We believe this is the first case with CSH that contained myeloblasts as well as erythroblasts in an otherwise healthy patient. A possible etiology was considered for the origin of precursor cells in his CSH. |
| first_indexed | 2024-04-13T15:05:01Z |
| format | Article |
| id | doaj.art-f2322fa63d5741ad991f27a08800b73e |
| institution | Directory Open Access Journal |
| issn | 2193-6358 2193-6366 |
| language | English |
| last_indexed | 2024-04-13T15:05:01Z |
| publishDate | 2014-06-01 |
| publisher | Georg Thieme Verlag KG |
| record_format | Article |
| series | Journal of Neurological Surgery Reports |
| spelling | doaj.art-f2322fa63d5741ad991f27a08800b73e2022-12-22T02:42:11ZengGeorg Thieme Verlag KGJournal of Neurological Surgery Reports2193-63582193-63662014-06-017501e129e13210.1055/s-0034-1376199Diffuse Presence of Myeloblasts in Chronic Subdural Hematoma of a Young Adult Patient without Systemic Hematologic DisorderShota Yokoyama0Toru Fukuhara1Yoichiro Namba2Shoji Asakura3Department of Neurological Surgery, National Hospital Organization Okayama Medical Center, Okayama, JapanDepartment of Neurological Surgery, National Hospital Organization Okayama Medical Center, Okayama, JapanDepartment of Neurological Surgery, National Hospital Organization Okayama Medical Center, Okayama, JapanDepartment of Hematology and Oncology, National Hospital Organization Okayama Medical Center, Okayama, JapanAbstract Objective Myeloblasts are rarely found in the composition of a chronic subdural hematoma (CSH), and reported cases with myeloblasts in CSH have all been associated with systemic hematologic disorders. We present a young man with CSH manifesting the diffuse presence of myeloblasts, although no systemic hematologic disorders were identified. Participant A 27-year-old man, complaining of a headache lasting for a few months, was diagnosed with right CSH, and the aspirated hematoma was sent for cytological evaluation because no apparent etiologic episode was found. The diffuse presence of precursor cells, such as myeloblasts and erythroblasts, mimicking the aspirated bone marrow, was confirmed. This finding was suggestive of a systemic hematologic disorder, although the systemic evaluations were negative. Results The patient's hematoma reaccumulated twice, and finally hematoma and enhanced dura were removed by craniotomy under general anesthesia. Further histologic evaluation did not show any precursor cells, and he has remained asymptomatic for > 2 years without any evidence of the hematologic disorder. Conclusion We believe this is the first case with CSH that contained myeloblasts as well as erythroblasts in an otherwise healthy patient. A possible etiology was considered for the origin of precursor cells in his CSH.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0034-1376199chronic subdural hematomaerythroblasthematologic disordermyeloblast |
| spellingShingle | Shota Yokoyama Toru Fukuhara Yoichiro Namba Shoji Asakura Diffuse Presence of Myeloblasts in Chronic Subdural Hematoma of a Young Adult Patient without Systemic Hematologic Disorder Journal of Neurological Surgery Reports chronic subdural hematoma erythroblast hematologic disorder myeloblast |
| title | Diffuse Presence of Myeloblasts in Chronic Subdural Hematoma of a Young Adult Patient without Systemic Hematologic Disorder |
| title_full | Diffuse Presence of Myeloblasts in Chronic Subdural Hematoma of a Young Adult Patient without Systemic Hematologic Disorder |
| title_fullStr | Diffuse Presence of Myeloblasts in Chronic Subdural Hematoma of a Young Adult Patient without Systemic Hematologic Disorder |
| title_full_unstemmed | Diffuse Presence of Myeloblasts in Chronic Subdural Hematoma of a Young Adult Patient without Systemic Hematologic Disorder |
| title_short | Diffuse Presence of Myeloblasts in Chronic Subdural Hematoma of a Young Adult Patient without Systemic Hematologic Disorder |
| title_sort | diffuse presence of myeloblasts in chronic subdural hematoma of a young adult patient without systemic hematologic disorder |
| topic | chronic subdural hematoma erythroblast hematologic disorder myeloblast |
| url | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0034-1376199 |
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