A novel miRNA biomarker panel associated with mortality in pediatric patients with ARDS

Abstract We identified a novel microRNA biomarker panel consisting of 6 microRNAs predicting mortality in pediatric acute respiratory distress syndrome patients. Each of the identified mRNA have potential mechanistic importance in acute respiratory distress syndrome and may lead to the development o...

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Main Authors: Lisa K. Lee, Mansoureh Eghbali, Anil Sapru
Format: Article
Language:English
Published: BMC 2021-06-01
Series:Respiratory Research
Subjects:
Online Access:https://doi.org/10.1186/s12931-021-01761-5
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author Lisa K. Lee
Mansoureh Eghbali
Anil Sapru
author_facet Lisa K. Lee
Mansoureh Eghbali
Anil Sapru
author_sort Lisa K. Lee
collection DOAJ
description Abstract We identified a novel microRNA biomarker panel consisting of 6 microRNAs predicting mortality in pediatric acute respiratory distress syndrome patients. Each of the identified mRNA have potential mechanistic importance in acute respiratory distress syndrome and may lead to the development of pharmacologic targets.
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spelling doaj.art-f23321fc129146d9bc58b716d455451b2022-12-21T21:09:00ZengBMCRespiratory Research1465-993X2021-06-012211510.1186/s12931-021-01761-5A novel miRNA biomarker panel associated with mortality in pediatric patients with ARDSLisa K. Lee0Mansoureh Eghbali1Anil Sapru2Department of Anesthesiology and Perioperative Medicine, David Geffen School of Medicine at UCLADepartment of Anesthesiology and Perioperative Medicine, David Geffen School of Medicine at UCLADivision of Pediatric Critical Care, Department of Pediatrics, David Geffen School of Medicine at UCLAAbstract We identified a novel microRNA biomarker panel consisting of 6 microRNAs predicting mortality in pediatric acute respiratory distress syndrome patients. Each of the identified mRNA have potential mechanistic importance in acute respiratory distress syndrome and may lead to the development of pharmacologic targets.https://doi.org/10.1186/s12931-021-01761-5miRNAARDSPediatricsBiomarkers
spellingShingle Lisa K. Lee
Mansoureh Eghbali
Anil Sapru
A novel miRNA biomarker panel associated with mortality in pediatric patients with ARDS
Respiratory Research
miRNA
ARDS
Pediatrics
Biomarkers
title A novel miRNA biomarker panel associated with mortality in pediatric patients with ARDS
title_full A novel miRNA biomarker panel associated with mortality in pediatric patients with ARDS
title_fullStr A novel miRNA biomarker panel associated with mortality in pediatric patients with ARDS
title_full_unstemmed A novel miRNA biomarker panel associated with mortality in pediatric patients with ARDS
title_short A novel miRNA biomarker panel associated with mortality in pediatric patients with ARDS
title_sort novel mirna biomarker panel associated with mortality in pediatric patients with ards
topic miRNA
ARDS
Pediatrics
Biomarkers
url https://doi.org/10.1186/s12931-021-01761-5
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