MDCT evaluation of coronary artery calcification in Nepalese population undergoing CT thorax examination for non-cardiac pathology

Background:Coronary artery calcification (CAC) is frequently encountered as incidental findings during CT evaluation of thorax; however, little is known about its magnitude and association with atherosclerotic risk factors in Nepalese population. The purpose of this study was to evaluate the frequen...

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Main Author: Mukesh Kumar Gupta
Format: Article
Language:English
Published: Manipal College of Medical Sciences, Pokhara 2015-02-01
Series:Asian Journal of Medical Sciences
Subjects:
Online Access:https://www.nepjol.info/index.php/AJMS/article/view/11205
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author Mukesh Kumar Gupta
author_facet Mukesh Kumar Gupta
author_sort Mukesh Kumar Gupta
collection DOAJ
description Background:Coronary artery calcification (CAC) is frequently encountered as incidental findings during CT evaluation of thorax; however, little is known about its magnitude and association with atherosclerotic risk factors in Nepalese population. The purpose of this study was to evaluate the frequency of incidental CAC in patients undergoing standard thoracic CT examination for non-cardiac pathology and to correlate it with risk factors for coronary atherosclerosis. Methods: A hospital based prospective cross-sectional study was conducted on 216 patients over 8 month duration. The coronary arteries were evaluated for calcification on 16-slice MDCT and the frequency of CAC was correlated with atherosclerotic risk factors viz. age, sex, diabetes mellitus, hypertension, smoking and obesity. Results: Incidental CAC was seen in 72(33.3%) of total 216 patients. The rates of CAC below 40, 40-60 and above 60 years age group were 0%, 31.6% and 43.9% respectively. The frequency of CAC in male and female were 35% and 31.2% for all ages, 43.6% and 20% for 40-60 years group, and 35.2% and 61.1% for above 60 years age group respectively. The frequency of CAC was higher in patients with diabetes mellitus (47.5%), hypertension (42.3%), smoking (43%) and obesity (38.9%). Conclusion: Incidental CAC was seen in 33.3% of the patients and it had significant association with advancing age, diabetes mellitus, hypertension and smoking. Rate of CAC was significantly higher in male for 40-60 years group but the frequency drastically increased in female for above 60 years group.
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spelling doaj.art-f236a527de7d4a51904410b07b33cdc62022-12-22T00:38:34ZengManipal College of Medical Sciences, PokharaAsian Journal of Medical Sciences2467-91002091-05762015-02-01644044https://doi.org/10.3126/ajms.v6i4.11205MDCT evaluation of coronary artery calcification in Nepalese population undergoing CT thorax examination for non-cardiac pathologyMukesh Kumar Gupta 0B.P. Koirala Institute of Health Sciences, Dharan,Background:Coronary artery calcification (CAC) is frequently encountered as incidental findings during CT evaluation of thorax; however, little is known about its magnitude and association with atherosclerotic risk factors in Nepalese population. The purpose of this study was to evaluate the frequency of incidental CAC in patients undergoing standard thoracic CT examination for non-cardiac pathology and to correlate it with risk factors for coronary atherosclerosis. Methods: A hospital based prospective cross-sectional study was conducted on 216 patients over 8 month duration. The coronary arteries were evaluated for calcification on 16-slice MDCT and the frequency of CAC was correlated with atherosclerotic risk factors viz. age, sex, diabetes mellitus, hypertension, smoking and obesity. Results: Incidental CAC was seen in 72(33.3%) of total 216 patients. The rates of CAC below 40, 40-60 and above 60 years age group were 0%, 31.6% and 43.9% respectively. The frequency of CAC in male and female were 35% and 31.2% for all ages, 43.6% and 20% for 40-60 years group, and 35.2% and 61.1% for above 60 years age group respectively. The frequency of CAC was higher in patients with diabetes mellitus (47.5%), hypertension (42.3%), smoking (43%) and obesity (38.9%). Conclusion: Incidental CAC was seen in 33.3% of the patients and it had significant association with advancing age, diabetes mellitus, hypertension and smoking. Rate of CAC was significantly higher in male for 40-60 years group but the frequency drastically increased in female for above 60 years group.https://www.nepjol.info/index.php/AJMS/article/view/11205coronary artery atherosclerosiscoronary artery calcificationincidentalmultidetector computed tomography
spellingShingle Mukesh Kumar Gupta
MDCT evaluation of coronary artery calcification in Nepalese population undergoing CT thorax examination for non-cardiac pathology
Asian Journal of Medical Sciences
coronary artery atherosclerosis
coronary artery calcification
incidental
multidetector computed tomography
title MDCT evaluation of coronary artery calcification in Nepalese population undergoing CT thorax examination for non-cardiac pathology
title_full MDCT evaluation of coronary artery calcification in Nepalese population undergoing CT thorax examination for non-cardiac pathology
title_fullStr MDCT evaluation of coronary artery calcification in Nepalese population undergoing CT thorax examination for non-cardiac pathology
title_full_unstemmed MDCT evaluation of coronary artery calcification in Nepalese population undergoing CT thorax examination for non-cardiac pathology
title_short MDCT evaluation of coronary artery calcification in Nepalese population undergoing CT thorax examination for non-cardiac pathology
title_sort mdct evaluation of coronary artery calcification in nepalese population undergoing ct thorax examination for non cardiac pathology
topic coronary artery atherosclerosis
coronary artery calcification
incidental
multidetector computed tomography
url https://www.nepjol.info/index.php/AJMS/article/view/11205
work_keys_str_mv AT mukeshkumargupta mdctevaluationofcoronaryarterycalcificationinnepalesepopulationundergoingctthoraxexaminationfornoncardiacpathology