Cough expired volume and airflow rates during sequential induced cough
Cough effectiveness is determined by a combination of volume of air expired and maximum expiratory airflow rate. Studies of cough sensitivity identify cough thresholds based on at least 2 or 5-cough re-accelerations to a stimulus, however to date no study has examined the interplay between the dis...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2013-07-01
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| Series: | Frontiers in Physiology |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fphys.2013.00167/full |
| _version_ | 1818683257285246976 |
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| author | Karen Wheeler Hegland Michelle S Troche Paul W Davenport |
| author_facet | Karen Wheeler Hegland Michelle S Troche Paul W Davenport |
| author_sort | Karen Wheeler Hegland |
| collection | DOAJ |
| description | Cough effectiveness is determined by a combination of volume of air expired and maximum expiratory airflow rate. Studies of cough sensitivity identify cough thresholds based on at least 2 or 5-cough re-accelerations to a stimulus, however to date no study has examined the interplay between the distribution of cough expired air and cough airflow rates for these induced sequential coughs. The goal of this study was to investigate the relationship between reflex cough re-accelerations, cough airflow and cough inspired and expired volume. Twenty adults (18–40 years, 4 men) volunteered for study participation, and were outfitted with a facemask in-line with a pneumotachograph and a one-way valve for capsaicin delivery on inspiration. Cough inspired and expired volume (Liters of air) as well as airflow parameters (peak expiratory flow rates L/s) were measured for each cough response. Results demonstrate significant linear relationships between cough expired volume, flow rates, and the total number of coughs produced. Thus, as the number of coughs in an epoch increase, the mechanical effectiveness of coughs within the epoch may decrease according to peak expiratory flow rates and cough expired volume, particularly for coughs comprised of more than 3 re-accelerations. |
| first_indexed | 2024-12-17T10:31:52Z |
| format | Article |
| id | doaj.art-f236fda7ac954150b94aaa6852258741 |
| institution | Directory Open Access Journal |
| issn | 1664-042X |
| language | English |
| last_indexed | 2024-12-17T10:31:52Z |
| publishDate | 2013-07-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Physiology |
| spelling | doaj.art-f236fda7ac954150b94aaa68522587412022-12-21T21:52:31ZengFrontiers Media S.A.Frontiers in Physiology1664-042X2013-07-01410.3389/fphys.2013.0016753118Cough expired volume and airflow rates during sequential induced coughKaren Wheeler Hegland0Michelle S Troche1Paul W Davenport2University of FloridaUniversity of FloridaUniversity of FloridaCough effectiveness is determined by a combination of volume of air expired and maximum expiratory airflow rate. Studies of cough sensitivity identify cough thresholds based on at least 2 or 5-cough re-accelerations to a stimulus, however to date no study has examined the interplay between the distribution of cough expired air and cough airflow rates for these induced sequential coughs. The goal of this study was to investigate the relationship between reflex cough re-accelerations, cough airflow and cough inspired and expired volume. Twenty adults (18–40 years, 4 men) volunteered for study participation, and were outfitted with a facemask in-line with a pneumotachograph and a one-way valve for capsaicin delivery on inspiration. Cough inspired and expired volume (Liters of air) as well as airflow parameters (peak expiratory flow rates L/s) were measured for each cough response. Results demonstrate significant linear relationships between cough expired volume, flow rates, and the total number of coughs produced. Thus, as the number of coughs in an epoch increase, the mechanical effectiveness of coughs within the epoch may decrease according to peak expiratory flow rates and cough expired volume, particularly for coughs comprised of more than 3 re-accelerations.http://journal.frontiersin.org/Journal/10.3389/fphys.2013.00167/fullCoughairway protectionreflex coughsequential coughcough effectiveness |
| spellingShingle | Karen Wheeler Hegland Michelle S Troche Paul W Davenport Cough expired volume and airflow rates during sequential induced cough Frontiers in Physiology Cough airway protection reflex cough sequential cough cough effectiveness |
| title | Cough expired volume and airflow rates during sequential induced cough |
| title_full | Cough expired volume and airflow rates during sequential induced cough |
| title_fullStr | Cough expired volume and airflow rates during sequential induced cough |
| title_full_unstemmed | Cough expired volume and airflow rates during sequential induced cough |
| title_short | Cough expired volume and airflow rates during sequential induced cough |
| title_sort | cough expired volume and airflow rates during sequential induced cough |
| topic | Cough airway protection reflex cough sequential cough cough effectiveness |
| url | http://journal.frontiersin.org/Journal/10.3389/fphys.2013.00167/full |
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