Chp1 is a dedicated chaperone at the ribosome that safeguards eEF1A biogenesis

Chp1 is a dedicated chaperone at the ribosome that safeguards eEF1A biogenesis

Abstract Cotranslational protein folding depends on general chaperones that engage highly diverse nascent chains at the ribosomes. Here we discover a dedicated ribosome-associated chaperone, Chp1, that rewires the cotranslational folding machinery to assist in the challenging biogenesis of abundantl...

Full description

Bibliographic Details
Main Authors: Melania Minoia, Jany Quintana-Cordero, Katharina Jetzinger, Ilgin Eser Kotan, Kathryn Jane Turnbull, Michela Ciccarelli, Anna E. Masser, Dorina Liebers, Eloïse Gouarin, Marius Czech, Vasili Hauryliuk, Bernd Bukau, Günter Kramer, Claes Andréasson
Format: Article
Language:English
Published: Nature Portfolio 2024-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-45645-w

Internet

https://doi.org/10.1038/s41467-024-45645-w

Similar Items