Ulipristal Acetate Interferes With Actin Remodeling Induced by 17β-Estradiol and Progesterone in Human Endometrial Stromal Cells

Ulipristal Acetate Interferes With Actin Remodeling Induced by 17β-Estradiol and Progesterone in Human Endometrial Stromal Cells

Ulipristal acetate (UPA) is a selective progesterone receptor modulator (SPRM) used for emergency contraception and for the medical management of symptomatic uterine fibroids (UF). Treatment with UPA turns in amenorrhea and UF volume reduction. Treatment with UPA is associated with the frequent deve...

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Bibliographic Details
Main Authors: Jorge E. Shortrede, Maria M. Montt-Guevara, Gisela Pennacchio, Michele Finiguerra, Andrea Giannini, Alessandro D. Genazzani, Tommaso Simoncini
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Endocrinology
Subjects:
Ulipristal acetate (UPA)
endometrial stromal cells (ESC)
progesterone (P4)
17β-estradiol (E2)
actin remodeling
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2018.00350/full

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