Sedation Is Associated with Higher Polyp and Adenoma Detection Rates during Colonoscopy: A Retrospective Cohort Study
Background and Aims. Currently sedation is a common practice in colonoscopy to reduce pain of patients and improve the operator satisfaction, whereas its impact on examination quality, especially adenoma detection rate (ADR) is still controversial. Thus, we aimed to investigate the association of se...
| Main Authors: | , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Hindawi Limited
2023-01-01
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| Series: | Gastroenterology Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2023/1172478 |
| _version_ | 1826992816645996544 |
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| author | Chenghu Xu Dehua Tang Ying Xie Muhan Ni Min Chen Yonghua Shen Xiaotan Dou Lin Zhou Guifang Xu Lei Wang Ying Lv Shu Zhang Xiaoping Zou |
| author_facet | Chenghu Xu Dehua Tang Ying Xie Muhan Ni Min Chen Yonghua Shen Xiaotan Dou Lin Zhou Guifang Xu Lei Wang Ying Lv Shu Zhang Xiaoping Zou |
| author_sort | Chenghu Xu |
| collection | DOAJ |
| description | Background and Aims. Currently sedation is a common practice in colonoscopy to reduce pain of patients and improve the operator satisfaction, whereas its impact on examination quality, especially adenoma detection rate (ADR) is still controversial. Thus, we aimed to investigate the association of sedation with ADR. Methods. Consecutive patients receiving colonoscopy between January 2017 and January 2020 at the Nanjing Drum Tower Hospital, Nanjing, China, were collected. Univariate and multivariate logistic regression models were performed to investigate the association between sedation and ADR. Subgroup analysis and propensity score matching (PSM) analysis, as sensitivity analysis, were performed to validate the independent effect. Results. The ADR was significantly higher in cases with sedation (ADR: 36.9% vs. 29.1%, odds ratio [OR]: 1.42, 95% confidence interval [CI]: 1.31–1.55, P<0.001). Multivariate analysis showed that the sedation was an independent factor associated with ADR (OR: 1.49, 95% CI: 1.35–1.65, P<0.001). The effect was consistent in subgroup analyses (P>0.05) and PSM analysis (ADR: 37.6% vs. 29.1%, OR: 1.47, 95% CI: 1.33–1.63, P<0.001). Conclusion. Sedation was associated with a higher polyp and ADR s during colonoscopy, which can promote the quality of colonoscopy. |
| first_indexed | 2024-04-10T05:26:23Z |
| format | Article |
| id | doaj.art-f23a035219614754890f054fe484e3ab |
| institution | Directory Open Access Journal |
| issn | 1687-630X |
| language | English |
| last_indexed | 2025-02-18T08:55:28Z |
| publishDate | 2023-01-01 |
| publisher | Hindawi Limited |
| record_format | Article |
| series | Gastroenterology Research and Practice |
| spelling | doaj.art-f23a035219614754890f054fe484e3ab2024-11-02T23:56:13ZengHindawi LimitedGastroenterology Research and Practice1687-630X2023-01-01202310.1155/2023/1172478Sedation Is Associated with Higher Polyp and Adenoma Detection Rates during Colonoscopy: A Retrospective Cohort StudyChenghu Xu0Dehua Tang1Ying Xie2Muhan Ni3Min Chen4Yonghua Shen5Xiaotan Dou6Lin Zhou7Guifang Xu8Lei Wang9Ying Lv10Shu Zhang11Xiaoping Zou12Department of GastroenterologyDepartment of GastroenterologyDepartment of GastroenterologyDepartment of GastroenterologyDepartment of GastroenterologyDepartment of GastroenterologyDepartment of GastroenterologyDepartment of GastroenterologyDepartment of GastroenterologyDepartment of GastroenterologyDepartment of GastroenterologyDepartment of GastroenterologyDepartment of GastroenterologyBackground and Aims. Currently sedation is a common practice in colonoscopy to reduce pain of patients and improve the operator satisfaction, whereas its impact on examination quality, especially adenoma detection rate (ADR) is still controversial. Thus, we aimed to investigate the association of sedation with ADR. Methods. Consecutive patients receiving colonoscopy between January 2017 and January 2020 at the Nanjing Drum Tower Hospital, Nanjing, China, were collected. Univariate and multivariate logistic regression models were performed to investigate the association between sedation and ADR. Subgroup analysis and propensity score matching (PSM) analysis, as sensitivity analysis, were performed to validate the independent effect. Results. The ADR was significantly higher in cases with sedation (ADR: 36.9% vs. 29.1%, odds ratio [OR]: 1.42, 95% confidence interval [CI]: 1.31–1.55, P<0.001). Multivariate analysis showed that the sedation was an independent factor associated with ADR (OR: 1.49, 95% CI: 1.35–1.65, P<0.001). The effect was consistent in subgroup analyses (P>0.05) and PSM analysis (ADR: 37.6% vs. 29.1%, OR: 1.47, 95% CI: 1.33–1.63, P<0.001). Conclusion. Sedation was associated with a higher polyp and ADR s during colonoscopy, which can promote the quality of colonoscopy.http://dx.doi.org/10.1155/2023/1172478 |
| spellingShingle | Chenghu Xu Dehua Tang Ying Xie Muhan Ni Min Chen Yonghua Shen Xiaotan Dou Lin Zhou Guifang Xu Lei Wang Ying Lv Shu Zhang Xiaoping Zou Sedation Is Associated with Higher Polyp and Adenoma Detection Rates during Colonoscopy: A Retrospective Cohort Study Gastroenterology Research and Practice |
| title | Sedation Is Associated with Higher Polyp and Adenoma Detection Rates during Colonoscopy: A Retrospective Cohort Study |
| title_full | Sedation Is Associated with Higher Polyp and Adenoma Detection Rates during Colonoscopy: A Retrospective Cohort Study |
| title_fullStr | Sedation Is Associated with Higher Polyp and Adenoma Detection Rates during Colonoscopy: A Retrospective Cohort Study |
| title_full_unstemmed | Sedation Is Associated with Higher Polyp and Adenoma Detection Rates during Colonoscopy: A Retrospective Cohort Study |
| title_short | Sedation Is Associated with Higher Polyp and Adenoma Detection Rates during Colonoscopy: A Retrospective Cohort Study |
| title_sort | sedation is associated with higher polyp and adenoma detection rates during colonoscopy a retrospective cohort study |
| url | http://dx.doi.org/10.1155/2023/1172478 |
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