Osseointegration of Titanium Implants in Onlay of Cerament™, a New Ceramic Bone Substitute
The purpose was to investigate whether a new biphasic and injectable ceramic bone substitute Cerament™ that rapidly remodels to bone, may contribute to the retention of titanium implant screws during the healing period, and to analyze the pattern of bone formation around titanium implants.Titanium s...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2016-01-01
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| Series: | Journal of Functional Biomaterials |
| Subjects: | |
| Online Access: | http://www.mdpi.com/2079-4983/7/1/2 |
| _version_ | 1798006707754893312 |
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| author | Anna Truedsson Jian-Sheng Wang Pia Lindberg Gunnar Warfvinge |
| author_facet | Anna Truedsson Jian-Sheng Wang Pia Lindberg Gunnar Warfvinge |
| author_sort | Anna Truedsson |
| collection | DOAJ |
| description | The purpose was to investigate whether a new biphasic and injectable ceramic bone substitute Cerament™ that rapidly remodels to bone, may contribute to the retention of titanium implant screws during the healing period, and to analyze the pattern of bone formation around titanium implants.Titanium screws were implanted in rat tibiae and embedded with or without Cerament™ on the cortical surface. Torsional resistance was measured after 1 day, and after 6 and 12 weeks. Implant areas without bone substitute were analyzed histologically for comparison. The torsional resistance increased over time as the screws were osseointegrated. There was no difference in resistance between screws embedded in the bone substitute and control screws. The bone apposition was more pronounced on the proximal side of the screw than on the distal side. Cerament™ is capable of conducting bone growth from a cortical bone surface. The newly formed bone in this application does not significantly add to the osseointegrative strength of the implant screw, as measured by torque resistance, during the first 12 weeks. |
| first_indexed | 2024-04-11T12:59:59Z |
| format | Article |
| id | doaj.art-f23b45b6332f4affbfbdf290f88932a3 |
| institution | Directory Open Access Journal |
| issn | 2079-4983 |
| language | English |
| last_indexed | 2024-04-11T12:59:59Z |
| publishDate | 2016-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Functional Biomaterials |
| spelling | doaj.art-f23b45b6332f4affbfbdf290f88932a32022-12-22T04:22:59ZengMDPI AGJournal of Functional Biomaterials2079-49832016-01-0171210.3390/jfb7010002jfb7010002Osseointegration of Titanium Implants in Onlay of Cerament™, a New Ceramic Bone SubstituteAnna Truedsson0Jian-Sheng Wang1Pia Lindberg2Gunnar Warfvinge3Department of Oral Pathology, Faculty of Odontology, Malmö University, Malmö SE-205 06, SwedenDepartment of Orthopedics, Lund University Hospital, Lund SE-221 85, SwedenDepartment of Oral Pathology, Faculty of Odontology, Malmö University, Malmö SE-205 06, SwedenDepartment of Oral Pathology, Faculty of Odontology, Malmö University, Malmö SE-205 06, SwedenThe purpose was to investigate whether a new biphasic and injectable ceramic bone substitute Cerament™ that rapidly remodels to bone, may contribute to the retention of titanium implant screws during the healing period, and to analyze the pattern of bone formation around titanium implants.Titanium screws were implanted in rat tibiae and embedded with or without Cerament™ on the cortical surface. Torsional resistance was measured after 1 day, and after 6 and 12 weeks. Implant areas without bone substitute were analyzed histologically for comparison. The torsional resistance increased over time as the screws were osseointegrated. There was no difference in resistance between screws embedded in the bone substitute and control screws. The bone apposition was more pronounced on the proximal side of the screw than on the distal side. Cerament™ is capable of conducting bone growth from a cortical bone surface. The newly formed bone in this application does not significantly add to the osseointegrative strength of the implant screw, as measured by torque resistance, during the first 12 weeks.http://www.mdpi.com/2079-4983/7/1/2animal modelbone substituteshistological analysisosseointegration |
| spellingShingle | Anna Truedsson Jian-Sheng Wang Pia Lindberg Gunnar Warfvinge Osseointegration of Titanium Implants in Onlay of Cerament™, a New Ceramic Bone Substitute Journal of Functional Biomaterials animal model bone substitutes histological analysis osseointegration |
| title | Osseointegration of Titanium Implants in Onlay of Cerament™, a New Ceramic Bone Substitute |
| title_full | Osseointegration of Titanium Implants in Onlay of Cerament™, a New Ceramic Bone Substitute |
| title_fullStr | Osseointegration of Titanium Implants in Onlay of Cerament™, a New Ceramic Bone Substitute |
| title_full_unstemmed | Osseointegration of Titanium Implants in Onlay of Cerament™, a New Ceramic Bone Substitute |
| title_short | Osseointegration of Titanium Implants in Onlay of Cerament™, a New Ceramic Bone Substitute |
| title_sort | osseointegration of titanium implants in onlay of cerament™ a new ceramic bone substitute |
| topic | animal model bone substitutes histological analysis osseointegration |
| url | http://www.mdpi.com/2079-4983/7/1/2 |
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