Design and Construction of a Synthetic Nanobody Library: Testing Its Potential with a Single Selection Round Strategy

Design and Construction of a Synthetic Nanobody Library: Testing Its Potential with a Single Selection Round Strategy

Nanobodies (Nbs) are single domain antibody fragments derived from heavy-chain antibodies found in members of the Camelidae family. They have become a relevant class of biomolecules for many different applications because of several important advantages such as their small size, high solubility and...

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Bibliographic Details
Main Authors: María Angélica Contreras, Yunier Serrano-Rivero, Alaín González-Pose, Julieta Salazar-Uribe, Marcela Rubio-Carrasquilla, Matheus Soares-Alves, Natalie C. Parra, Frank Camacho-Casanova, Oliberto Sánchez-Ramos, Ernesto Moreno
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Molecules
Subjects:
nanobody
synthetic library
phage display
CDR randomization
biopanning
tumor necrosis factor
Online Access:https://www.mdpi.com/1420-3049/28/9/3708

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