pSONIC: Ploidy-aware Syntenic Orthologous Networks Identified via Collinearity

AbstractWith the rapid rise in availability of high-quality genomes for closely related species, methods for orthology inference that incorporate synteny are increasingly useful. Polyploidy perturbs the 1:1 expected frequencies of orthologs between two species, complicating the identification of ort...

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Main Authors: Justin L Conover, Joel Sharbrough, Jonathan F Wendel
Format: Article
Language:English
Published: Oxford University Press 2021-05-01
Series:G3: Genes, Genomes, Genetics
Online Access:https://academic.oup.com/g3journal/article-lookup/doi/10.1093/g3journal/jkab170
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author Justin L Conover
Joel Sharbrough
Jonathan F Wendel
author_facet Justin L Conover
Joel Sharbrough
Jonathan F Wendel
author_sort Justin L Conover
collection DOAJ
description AbstractWith the rapid rise in availability of high-quality genomes for closely related species, methods for orthology inference that incorporate synteny are increasingly useful. Polyploidy perturbs the 1:1 expected frequencies of orthologs between two species, complicating the identification of orthologs. Here we present a method of ortholog inference, Ploidy-aware Syntenic Orthologous Networks Identified via Collinearity (pSONIC). We demonstrate the utility of pSONIC using four species in the cotton tribe (Gossypieae
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spelling doaj.art-f243635adf6a49f0b9c75cac299113862022-12-21T23:48:41ZengOxford University PressG3: Genes, Genomes, Genetics2160-18362021-05-0111810.1093/g3journal/jkab170pSONIC: Ploidy-aware Syntenic Orthologous Networks Identified via CollinearityJustin L Conover0https://orcid.org/0000-0002-3558-6000Joel Sharbrough1https://orcid.org/0000-0002-3642-1662Jonathan F Wendel2https://orcid.org/0000-0003-2258-5081Department of Ecology, Evolution, and Organismal Biology, Iowa State University, Ames, IA 50011, USABiology Department, Colorado State University, Fort Collins, CO 80521, USADepartment of Ecology, Evolution, and Organismal Biology, Iowa State University, Ames, IA 50011, USAAbstractWith the rapid rise in availability of high-quality genomes for closely related species, methods for orthology inference that incorporate synteny are increasingly useful. Polyploidy perturbs the 1:1 expected frequencies of orthologs between two species, complicating the identification of orthologs. Here we present a method of ortholog inference, Ploidy-aware Syntenic Orthologous Networks Identified via Collinearity (pSONIC). We demonstrate the utility of pSONIC using four species in the cotton tribe (Gossypieaehttps://academic.oup.com/g3journal/article-lookup/doi/10.1093/g3journal/jkab170
spellingShingle Justin L Conover
Joel Sharbrough
Jonathan F Wendel
pSONIC: Ploidy-aware Syntenic Orthologous Networks Identified via Collinearity
G3: Genes, Genomes, Genetics
title pSONIC: Ploidy-aware Syntenic Orthologous Networks Identified via Collinearity
title_full pSONIC: Ploidy-aware Syntenic Orthologous Networks Identified via Collinearity
title_fullStr pSONIC: Ploidy-aware Syntenic Orthologous Networks Identified via Collinearity
title_full_unstemmed pSONIC: Ploidy-aware Syntenic Orthologous Networks Identified via Collinearity
title_short pSONIC: Ploidy-aware Syntenic Orthologous Networks Identified via Collinearity
title_sort psonic ploidy aware syntenic orthologous networks identified via collinearity
url https://academic.oup.com/g3journal/article-lookup/doi/10.1093/g3journal/jkab170
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