The Role of the Vitamin D Receptor in the Pathogenesis, Prognosis, and Treatment of Cutaneous Melanoma

The Role of the Vitamin D Receptor in the Pathogenesis, Prognosis, and Treatment of Cutaneous Melanoma

Melanoma is the malignant transformation of melanocytes and represents the most lethal form of skin cancer. While early-stage melanoma localized to the skin can be cured with surgical excision, metastatic melanoma often requires a multi-pronged approach and even then can exhibit treatment resistance...

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Bibliographic Details
Main Authors: Alyssa L. Becker, Evan L. Carpenter, Andrzej T. Slominski, Arup K. Indra
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Oncology
Subjects:
melanoma
vitamin D receptor (VDR)
vitamin D3 metabolite
therapy
pathogenesis
tumor microenvironment
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.743667/full

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