Characterization and antitumor efficacy of poly(L-lactid acid)-based etoposide-loaded implants

Characterization and antitumor efficacy of poly(L-lactid acid)-based etoposide-loaded implants

Etoposide is widely used in the chemotherapy of a variety of malignancies. But the strong lipophilicity, poor bioavailability, and severe side effects of etoposide limit its clinical application. The aim of this study was to develop sustained-release etoposide-loaded implants and evaluate antitumor...

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Bibliographic Details
Main Authors: Li Gao, Chuanqi Xie, Yuzhi Du, Xiaodong Wang, Erkang Xuan, Xiuxiu Liu, Yang Zhao, Jianjian Xu, Lan Luo
Format: Article
Language:English
Published: Taylor & Francis Group 2017-01-01
Series:Drug Delivery
Subjects:
etoposide
implant
poly(l-lactid acid)
sustained release
intratumoral chemotherapy
Online Access:http://dx.doi.org/10.1080/10717544.2017.1321063

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