Clinical signs of tuberculosis relapses in HIV patients

The objective: to study clinical manifestations of tuberculosis relapses and their treatment outcomes in patients with HIV infection.Subjects and Methods. 132 medical records of patients with tuberculosis relapses were analyzed; 69 of them were HIV-positive and 63 were HIV-negative. All of them were...

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Main Authors: E. Yu. Zorkаltsevа, Yu. O. Egorovа
Format: Article
Language:Russian
Published: New Terra Publishing House 2020-07-01
Series:Туберкулез и болезни лёгких
Subjects:
Online Access:https://www.tibl-journal.com/jour/article/view/1432
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author E. Yu. Zorkаltsevа
Yu. O. Egorovа
author_facet E. Yu. Zorkаltsevа
Yu. O. Egorovа
author_sort E. Yu. Zorkаltsevа
collection DOAJ
description The objective: to study clinical manifestations of tuberculosis relapses and their treatment outcomes in patients with HIV infection.Subjects and Methods. 132 medical records of patients with tuberculosis relapses were analyzed; 69 of them were HIV-positive and 63 were HIV-negative. All of them were admitted to Irkutsk Regional Clinical Tuberculosis Hospital from 2016 to 2019, and then continued treatment of tuberculosis on the out-patient basis. Treatment efficacy was assessed in February 2020.Results. More severe clinical forms of tuberculosis relapses were typical of HIV patients including generalized forms affecting the central nervous system. Therefore, among these patients, the mortality rate is significantly higher (24.6%) than in tuberculosis relapses with no concurrent HIV infection (6.3%), p ≤ 0.05.
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spelling doaj.art-f24dcf71e46d43da89ce34ac113515002025-03-02T11:22:32ZrusNew Terra Publishing HouseТуберкулез и болезни лёгких2075-12302542-15062020-07-01986323510.21292/2075-1230-2020-98-6-32-351431Clinical signs of tuberculosis relapses in HIV patientsE. Yu. Zorkаltsevа0Yu. O. Egorovа1Irkutsk State Medical Academy of Postgraduate Education – Branch of Russian Medical Academy of Continuing Professional EducationIrkutsk State Medical Academy of Postgraduate Education – Branch of Russian Medical Academy of Continuing Professional EducationThe objective: to study clinical manifestations of tuberculosis relapses and their treatment outcomes in patients with HIV infection.Subjects and Methods. 132 medical records of patients with tuberculosis relapses were analyzed; 69 of them were HIV-positive and 63 were HIV-negative. All of them were admitted to Irkutsk Regional Clinical Tuberculosis Hospital from 2016 to 2019, and then continued treatment of tuberculosis on the out-patient basis. Treatment efficacy was assessed in February 2020.Results. More severe clinical forms of tuberculosis relapses were typical of HIV patients including generalized forms affecting the central nervous system. Therefore, among these patients, the mortality rate is significantly higher (24.6%) than in tuberculosis relapses with no concurrent HIV infection (6.3%), p ≤ 0.05.https://www.tibl-journal.com/jour/article/view/1432tuberculosishiv infectiontuberculosis relapsesoutcomes of tuberculosis
spellingShingle E. Yu. Zorkаltsevа
Yu. O. Egorovа
Clinical signs of tuberculosis relapses in HIV patients
Туберкулез и болезни лёгких
tuberculosis
hiv infection
tuberculosis relapses
outcomes of tuberculosis
title Clinical signs of tuberculosis relapses in HIV patients
title_full Clinical signs of tuberculosis relapses in HIV patients
title_fullStr Clinical signs of tuberculosis relapses in HIV patients
title_full_unstemmed Clinical signs of tuberculosis relapses in HIV patients
title_short Clinical signs of tuberculosis relapses in HIV patients
title_sort clinical signs of tuberculosis relapses in hiv patients
topic tuberculosis
hiv infection
tuberculosis relapses
outcomes of tuberculosis
url https://www.tibl-journal.com/jour/article/view/1432
work_keys_str_mv AT eyuzorkaltseva clinicalsignsoftuberculosisrelapsesinhivpatients
AT yuoegorova clinicalsignsoftuberculosisrelapsesinhivpatients