Non ictal onset zone: A window to ictal dynamics
The focal and network concepts of epilepsy present different aspects of electroclinical phenomenon of seizures. Here, we present a 23-year-old man undergoing surgical evaluation with left fronto-temporal electrocorticography (ECoG) and microelectrode-array (MEA) in the middle temporal gyrus (MTG). W...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2017-01-01
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| Series: | Epilepsy and Behavior Case Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2213323217300737 |
| _version_ | 1811204603338817536 |
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| author | Pegah Afra Sara J. Hanrahan Spencer Sterling Kellis Paul House |
| author_facet | Pegah Afra Sara J. Hanrahan Spencer Sterling Kellis Paul House |
| author_sort | Pegah Afra |
| collection | DOAJ |
| description | The focal and network concepts of epilepsy present different aspects of electroclinical phenomenon of seizures. Here, we present a 23-year-old man undergoing surgical evaluation with left fronto-temporal electrocorticography (ECoG) and microelectrode-array (MEA) in the middle temporal gyrus (MTG). We compare action-potential (AP) and local field potentials (LFP) recorded from MEA with ECoG. Seizure onset in the mesial-temporal lobe was characterized by changes in the pattern of AP-firing without clear changes in LFP or ECoG in MTG. This suggests simultaneous analysis of neuronal activity in differing spatial scales and frequency ranges provide complementary insights into how focal and network neurophysiological activity contribute to ictal activity. |
| first_indexed | 2024-04-12T03:16:57Z |
| format | Article |
| id | doaj.art-f24f6357764e42f8a9a6770c4b34cc1a |
| institution | Directory Open Access Journal |
| issn | 2213-3232 |
| language | English |
| last_indexed | 2024-04-12T03:16:57Z |
| publishDate | 2017-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Epilepsy and Behavior Case Reports |
| spelling | doaj.art-f24f6357764e42f8a9a6770c4b34cc1a2022-12-22T03:50:06ZengElsevierEpilepsy and Behavior Case Reports2213-32322017-01-018C12312710.1016/j.ebcr.2017.10.003Non ictal onset zone: A window to ictal dynamicsPegah Afra0Sara J. Hanrahan1Spencer Sterling Kellis2Paul House3Department of Neurology, School of Medicine, University of Utah, Salt Lake City, UT, United StatesColorado Neurological Institute, Englewood, CO, United StatesDivision of Biology, Caltech, Pasadena, CA, United StatesDepartment of Neurosurgery, School of Medicine, University of Utah, Salt Lake City, UT, United StatesThe focal and network concepts of epilepsy present different aspects of electroclinical phenomenon of seizures. Here, we present a 23-year-old man undergoing surgical evaluation with left fronto-temporal electrocorticography (ECoG) and microelectrode-array (MEA) in the middle temporal gyrus (MTG). We compare action-potential (AP) and local field potentials (LFP) recorded from MEA with ECoG. Seizure onset in the mesial-temporal lobe was characterized by changes in the pattern of AP-firing without clear changes in LFP or ECoG in MTG. This suggests simultaneous analysis of neuronal activity in differing spatial scales and frequency ranges provide complementary insights into how focal and network neurophysiological activity contribute to ictal activity.http://www.sciencedirect.com/science/article/pii/S2213323217300737Microelectrode arrayIctal dynamicsMicrogridSingle neuron recordingIctal onset |
| spellingShingle | Pegah Afra Sara J. Hanrahan Spencer Sterling Kellis Paul House Non ictal onset zone: A window to ictal dynamics Epilepsy and Behavior Case Reports Microelectrode array Ictal dynamics Microgrid Single neuron recording Ictal onset |
| title | Non ictal onset zone: A window to ictal dynamics |
| title_full | Non ictal onset zone: A window to ictal dynamics |
| title_fullStr | Non ictal onset zone: A window to ictal dynamics |
| title_full_unstemmed | Non ictal onset zone: A window to ictal dynamics |
| title_short | Non ictal onset zone: A window to ictal dynamics |
| title_sort | non ictal onset zone a window to ictal dynamics |
| topic | Microelectrode array Ictal dynamics Microgrid Single neuron recording Ictal onset |
| url | http://www.sciencedirect.com/science/article/pii/S2213323217300737 |
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