Giant infra and supratentorial medulloblastoma in an under 3 years old child

We report a very unusual case of giant medulloblastoma with supratentorial extension of a 3-year-old boy, who had been treated over a two-year period. As he was considered at the eleventh month of life, as a case out of surgical resources because of poor prognostic and a short life expectancy, the c...

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Main Authors: St. I. Florian, E. Mihut, D. Cernea, C. Abrudan, C. Suciu, Z. Andrasoni
Format: Article
Language:English
Published: London Academic Publishing 2007-03-01
Series:Romanian Neurosurgery
Subjects:
Online Access:https://journals.lapub.co.uk/index.php/roneurosurgery/article/view/383
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author St. I. Florian
E. Mihut
D. Cernea
C. Abrudan
C. Suciu
Z. Andrasoni
author_facet St. I. Florian
E. Mihut
D. Cernea
C. Abrudan
C. Suciu
Z. Andrasoni
author_sort St. I. Florian
collection DOAJ
description We report a very unusual case of giant medulloblastoma with supratentorial extension of a 3-year-old boy, who had been treated over a two-year period. As he was considered at the eleventh month of life, as a case out of surgical resources because of poor prognostic and a short life expectancy, the child was operated eight months later in our department despite the huge dimensions of infra and supratentorial tumoral extensions. Adequate chemotherapy regimen conducted to decrease and even neuroradiological disappearance of some tumor reminiscence after subtotal surgical ablation. The purpose of this case study is to discuss certain aspects of the sequential surgical treatment and associate chemotherapy, and also to discuss where the limits are, if there are any in the multimodal treatment. We consider it a very illustrative case for what surgery along with adequate regimen of chemotherapy can obtain in patients under 3 years old with radiosensitive tumors: it prolongs survival over 3 years and makes children able to benefit from radiotherapy at appropriate age.
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spelling doaj.art-f252cf924c1e4c61a39c9886a29ec0482022-12-21T23:14:02ZengLondon Academic PublishingRomanian Neurosurgery1220-88412344-49592007-03-01141Giant infra and supratentorial medulloblastoma in an under 3 years old childSt. I. FlorianE. MihutD. CerneaC. AbrudanC. SuciuZ. AndrasoniWe report a very unusual case of giant medulloblastoma with supratentorial extension of a 3-year-old boy, who had been treated over a two-year period. As he was considered at the eleventh month of life, as a case out of surgical resources because of poor prognostic and a short life expectancy, the child was operated eight months later in our department despite the huge dimensions of infra and supratentorial tumoral extensions. Adequate chemotherapy regimen conducted to decrease and even neuroradiological disappearance of some tumor reminiscence after subtotal surgical ablation. The purpose of this case study is to discuss certain aspects of the sequential surgical treatment and associate chemotherapy, and also to discuss where the limits are, if there are any in the multimodal treatment. We consider it a very illustrative case for what surgery along with adequate regimen of chemotherapy can obtain in patients under 3 years old with radiosensitive tumors: it prolongs survival over 3 years and makes children able to benefit from radiotherapy at appropriate age.https://journals.lapub.co.uk/index.php/roneurosurgery/article/view/383medulloblastomamultiple stage surgerychemotherapy
spellingShingle St. I. Florian
E. Mihut
D. Cernea
C. Abrudan
C. Suciu
Z. Andrasoni
Giant infra and supratentorial medulloblastoma in an under 3 years old child
Romanian Neurosurgery
medulloblastoma
multiple stage surgery
chemotherapy
title Giant infra and supratentorial medulloblastoma in an under 3 years old child
title_full Giant infra and supratentorial medulloblastoma in an under 3 years old child
title_fullStr Giant infra and supratentorial medulloblastoma in an under 3 years old child
title_full_unstemmed Giant infra and supratentorial medulloblastoma in an under 3 years old child
title_short Giant infra and supratentorial medulloblastoma in an under 3 years old child
title_sort giant infra and supratentorial medulloblastoma in an under 3 years old child
topic medulloblastoma
multiple stage surgery
chemotherapy
url https://journals.lapub.co.uk/index.php/roneurosurgery/article/view/383
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AT dcernea giantinfraandsupratentorialmedulloblastomainanunder3yearsoldchild
AT cabrudan giantinfraandsupratentorialmedulloblastomainanunder3yearsoldchild
AT csuciu giantinfraandsupratentorialmedulloblastomainanunder3yearsoldchild
AT zandrasoni giantinfraandsupratentorialmedulloblastomainanunder3yearsoldchild