Evaluation of 2′-Deoxy-2′-Flouro-5-Methyl-1-β--Arabinofuranosyluracil as a Potential Gene Imaging Agent for Expression In Vivo
2′-Deoxy-2′-flouro-5-methyl-1-β- d -arabinofuranosyluracil (FMAU) has been evaluated in HT-29 cells as a potential positron emission tomography (PET) radiotracer for imaging HSV-tk gene expression in vivo. In vitro experiments demonstrate that the accumulation of [ 14 C]-FMAU in HSV-tk -expressing c...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
SAGE Publications
2002-04-01
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| Series: | Molecular Imaging |
| Online Access: | https://doi.org/10.1162/15353500200202100 |