Motor neuron diseases in the University Hospital of Fortaleza (Northeastern Brazil): a clinico-demographic analysis of 87 cases
In this retrospective (1980-1998) study, we have analyzed clinico-demographically, from the records of the University Hospital of Fortaleza (Brazil), a group of 87 patients showing signs and symptoms of motor neuron diseases (MNDs). Their diagnosis was determined clinically and laboratorially. The W...
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| Format: | Article |
| Language: | English |
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Academia Brasileira de Neurologia (ABNEURO)
2000-12-01
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| Series: | Arquivos de Neuro-Psiquiatria |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2000000600002&tlng=en |
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| author | CARLOS M. DE CASTRO-COSTA REINALDO B. ORIÁ OTONI C. DO VALE JOSÉ ARNALDO M. DE ARRUDA WAGNER G. HORTA JOSÉ ARTUR C. D'ALMEIDA TEREZINHA J.T. SANTOS RODRIGO S.N. RAMOS MARCUS A.C. GIFONI |
| author_facet | CARLOS M. DE CASTRO-COSTA REINALDO B. ORIÁ OTONI C. DO VALE JOSÉ ARNALDO M. DE ARRUDA WAGNER G. HORTA JOSÉ ARTUR C. D'ALMEIDA TEREZINHA J.T. SANTOS RODRIGO S.N. RAMOS MARCUS A.C. GIFONI |
| author_sort | CARLOS M. DE CASTRO-COSTA |
| collection | DOAJ |
| description | In this retrospective (1980-1998) study, we have analyzed clinico-demographically, from the records of the University Hospital of Fortaleza (Brazil), a group of 87 patients showing signs and symptoms of motor neuron diseases (MNDs). Their diagnosis was determined clinically and laboratorially. The WFN criteria were used for amyotrophic lateral sclerosis (ALS) diagnosis. The clinico-demographic analysis of the 87 cases of MNDs showed that 4 were diagnosed as spinal muscular atrophy (SMA), 5 cases as ALS subsets: 2 as progressive bulbar paralysis (PBP), 2 as progressive muscular atrophy (PMA) and 1 as monomelic amyotrophy (MA), and 78 cases of ALS. The latter comprised 51 males and 27 females, with a mean age of 42.02 years. They were sub-divided into 4 groups according to age: from 15 to 29 years (n= 17), 30 to 39 years (n= 18), 40 to 69 years (n= 39) and 70 to 78 years (n= 4). From the 78 ALS patients, 76 were of the classic sporadic form whilst only 2 were of the familial form. The analysis of the 87 patients with MNDs from the University Hospital of Fortaleza showed a predominance of ALS patients, with a high number of cases of juvenile and early onset adult sporadic ALS. |
| first_indexed | 2024-12-17T20:08:14Z |
| format | Article |
| id | doaj.art-f256cb1326ba4c24af2393b503882f19 |
| institution | Directory Open Access Journal |
| issn | 1678-4227 |
| language | English |
| last_indexed | 2024-12-17T20:08:14Z |
| publishDate | 2000-12-01 |
| publisher | Academia Brasileira de Neurologia (ABNEURO) |
| record_format | Article |
| series | Arquivos de Neuro-Psiquiatria |
| spelling | doaj.art-f256cb1326ba4c24af2393b503882f192022-12-21T21:34:17ZengAcademia Brasileira de Neurologia (ABNEURO)Arquivos de Neuro-Psiquiatria1678-42272000-12-01584986989Motor neuron diseases in the University Hospital of Fortaleza (Northeastern Brazil): a clinico-demographic analysis of 87 casesCARLOS M. DE CASTRO-COSTA0REINALDO B. ORIÁ1OTONI C. DO VALE2JOSÉ ARNALDO M. DE ARRUDA3WAGNER G. HORTA4JOSÉ ARTUR C. D'ALMEIDA5TEREZINHA J.T. SANTOS6RODRIGO S.N. RAMOS7MARCUS A.C. GIFONI8Federal University of CearáFederal University of CearáFederal University of CearáFederal University of CearáFederal University of CearáFederal University of CearáFederal University of CearáFederal University of CearáFederal University of CearáIn this retrospective (1980-1998) study, we have analyzed clinico-demographically, from the records of the University Hospital of Fortaleza (Brazil), a group of 87 patients showing signs and symptoms of motor neuron diseases (MNDs). Their diagnosis was determined clinically and laboratorially. The WFN criteria were used for amyotrophic lateral sclerosis (ALS) diagnosis. The clinico-demographic analysis of the 87 cases of MNDs showed that 4 were diagnosed as spinal muscular atrophy (SMA), 5 cases as ALS subsets: 2 as progressive bulbar paralysis (PBP), 2 as progressive muscular atrophy (PMA) and 1 as monomelic amyotrophy (MA), and 78 cases of ALS. The latter comprised 51 males and 27 females, with a mean age of 42.02 years. They were sub-divided into 4 groups according to age: from 15 to 29 years (n= 17), 30 to 39 years (n= 18), 40 to 69 years (n= 39) and 70 to 78 years (n= 4). From the 78 ALS patients, 76 were of the classic sporadic form whilst only 2 were of the familial form. The analysis of the 87 patients with MNDs from the University Hospital of Fortaleza showed a predominance of ALS patients, with a high number of cases of juvenile and early onset adult sporadic ALS.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2000000600002&tlng=enmotor neuron diseasesamyotrophic lateral sclerosisFortaleza (Brazil) |
| spellingShingle | CARLOS M. DE CASTRO-COSTA REINALDO B. ORIÁ OTONI C. DO VALE JOSÉ ARNALDO M. DE ARRUDA WAGNER G. HORTA JOSÉ ARTUR C. D'ALMEIDA TEREZINHA J.T. SANTOS RODRIGO S.N. RAMOS MARCUS A.C. GIFONI Motor neuron diseases in the University Hospital of Fortaleza (Northeastern Brazil): a clinico-demographic analysis of 87 cases Arquivos de Neuro-Psiquiatria motor neuron diseases amyotrophic lateral sclerosis Fortaleza (Brazil) |
| title | Motor neuron diseases in the University Hospital of Fortaleza (Northeastern Brazil): a clinico-demographic analysis of 87 cases |
| title_full | Motor neuron diseases in the University Hospital of Fortaleza (Northeastern Brazil): a clinico-demographic analysis of 87 cases |
| title_fullStr | Motor neuron diseases in the University Hospital of Fortaleza (Northeastern Brazil): a clinico-demographic analysis of 87 cases |
| title_full_unstemmed | Motor neuron diseases in the University Hospital of Fortaleza (Northeastern Brazil): a clinico-demographic analysis of 87 cases |
| title_short | Motor neuron diseases in the University Hospital of Fortaleza (Northeastern Brazil): a clinico-demographic analysis of 87 cases |
| title_sort | motor neuron diseases in the university hospital of fortaleza northeastern brazil a clinico demographic analysis of 87 cases |
| topic | motor neuron diseases amyotrophic lateral sclerosis Fortaleza (Brazil) |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2000000600002&tlng=en |
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