Processing of LtaS restricts LTA assembly and YSIRK preprotein trafficking into Staphylococcus aureus cross-walls

Processing of LtaS restricts LTA assembly and YSIRK preprotein trafficking into Staphylococcus aureus cross-walls

ABSTRACTSeptal membranes of Staphylococcus aureus serve as the site of secretion for precursors endowed with the YSIRK motif. Depletion of ltaS, a gene required for lipoteichoic acid (LTA) synthesis, results in the loss of restricted trafficking of YSIRK precursors to septal membranes. Here, we seek...

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Bibliographic Details
Main Authors: Amany M. Ibrahim, Muhammad S. Azam, Olaf Schneewind, Dominique Missiakas
Format: Article
Language:English
Published: American Society for Microbiology 2024-02-01
Series:mBio
Subjects:
Staphylococcus aureus
cross-wall
lipoteichoic acid synthase
gentiobiosyldiacylglycerol
signal peptidase
protein secretion
Online Access:https://journals.asm.org/doi/10.1128/mbio.02852-23

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