In vivo characterization of the activities of novel cyclodipeptide oxidases: new tools for increasing chemical diversity of bioproduced 2,5-diketopiperazines in Escherichia coli

In vivo characterization of the activities of novel cyclodipeptide oxidases: new tools for increasing chemical diversity of bioproduced 2,5-diketopiperazines in Escherichia coli

Abstract Background Cyclodipeptide oxidases (CDOs) are enzymes involved in the biosynthesis of 2,5-diketopiperazines, a class of naturally occurring compounds with a large range of pharmaceutical activities. CDOs belong to cyclodipeptide synthase (CDPS)-dependent pathways, in which they play an earl...

詳細記述

書誌詳細
主要な著者: Fabien Le Chevalier, Isabelle Correia, Lucrèce Matheron, Morgan Babin, Mireille Moutiez, Nicolas Canu, Muriel Gondry, Olivier Lequin, Pascal Belin
フォーマット: 論文
言語:English
出版事項: BMC 2020-09-01
シリーズ:Microbial Cell Factories
主題:
Synthetic biology
Combinatorial biosynthesis
Natural products
2,5-diketopiperazine
Cyclodipeptide synthase
Cyclodipeptide oxidase
オンライン･アクセス:http://link.springer.com/article/10.1186/s12934-020-01432-y

インターネット

http://link.springer.com/article/10.1186/s12934-020-01432-y

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