Tolerogenic Transcriptional Signatures of Steady-State and Pathogen-Induced Dendritic Cells
Dendritic cells (DCs) are key directors of tolerogenic and immunogenic immune responses. During the steady state, DCs maintain T cell tolerance to self-antigens by multiple mechanisms including inducing anergy, deletion, and Treg activity. All of these mechanisms help to prevent autoimmune diseases...
| Главные авторы: | , , , , , , |
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| Формат: | Статья |
| Язык: | English |
| Опубликовано: |
Frontiers Media S.A.
2018-02-01
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| Серии: | Frontiers in Immunology |
| Предметы: | |
| Online-ссылка: | http://journal.frontiersin.org/article/10.3389/fimmu.2018.00333/full |