Synthesis, Characterization and Biological Evaluation of Magnolol and Honokiol Derivatives with 1,3,5-Triazine of Metformin Cyclization

Synthesis, Characterization and Biological Evaluation of Magnolol and Honokiol Derivatives with 1,3,5-Triazine of Metformin Cyclization

Herein, we sought to evaluate the contribution of the 1,3,5-triazine ring through the metformin cyclization unit to the biological activity of magnolol and honokiol-conjugates. One of the phenolic OH groups of magnolol or honokiol was replaced by a 1,3,5-triazine ring to further explore their synthe...

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Bibliographic Details
Main Authors: Cui Ren, Juanxia Wang, Youzhen Tan, Mingxin Guo, Jieqing Guo, Ying Liu, Xia Wu, Yifan Feng
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Molecules
Subjects:
magnolol
honokiol
metformin
chemical synthesis
biological activity
Online Access:https://www.mdpi.com/1420-3049/25/24/5779

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