Downregulation of demethylase FTO inhibits proliferation of human liver cancer cell line HepG2

Downregulation of demethylase FTO inhibits proliferation of human liver cancer cell line HepG2

Objective To explore the mechanism of the demethylase fat mass and obesity associatal(FTO) gene on the proliferation of human liver cancer cell line HepG2. Methods HepG2 cells were divided into the control group, FTO group (transfected with FTO over-expression plasmid), si-FTO group (transfected wit...

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Bibliographic Details
Main Author: LU Huiying, WANG Jianguo
Format: Article
Language:zho
Published: Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College. 2024-02-01
Series:Jichu yixue yu linchuang
Subjects:
demethylase|fat mass and obesity associated(fto) protein|forkhead box protein 1(foxo1)|hepatocellular carcinoma|apoptosis
Online Access:http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/1001-6325-2024-44-2-185.pdf

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